Sr. Research Associate

Piper Companies; Cambridge (MA); On-site; USD 80,000 - 100,000; Full time

Benefits offered by this job

PTO

Medical Insurance

Dental Insurance

Vision Insurance

401K

Tuition Reimbursement

Sick Leave

Job summary

Zachary Piper Solutions seeks a Sr Research Associate to support a biotech company focused on next-generation immune cell therapies at our Cambridge, MA site. The role executes cell culture, differentiation, molecular biology, and process development to advance a stem cell–derived therapy from preclinical toward commercialization.

Responsibilities include stem cell culture, flow cytometry, RT-qPCR, ddPCR, ELISA, IHC/IF, data analysis, and protocol troubleshooting while ensuring safety and

Qualifications

• 2+ years of experience in pluripotent stem cell biology, regenerative medicine, cell therapy or related biotech field.
• Hands-on experience with hPSC culture and differentiation, RT-qPCR, ddPCR, flow cytometry, ELISA.
• Strong analytical, organizational and data-analysis skills; ability to work independently and in a team.

Responsibilities

• Perform hPSC/iPSC culture, maintenance, differentiation, and characterization experiments.
• Execute molecular and cellular assays including flow cytometry, RT-qPCR, ddPCR, ELISA, IHC and IF analyses.
• Support cell engineering studies; evaluate differentiation, functionality, and process optimization.
• Analyze data, troubleshoot protocols, contribute to process standardization, and present findings.
• Maintain lab operations, ensure safety/compliance, manage supplies, and train personnel.

Skills

Pluripotent stem cell biology

Cell culture

Molecular biology

Flow cytometry

RT-qPCR

ddPCR

ELISA

Data analysis

Troubleshooting

Communication

Education

Bachelor’s or Master’s degree in Biology or related field

Tools

Immunohistochemistry

Immunofluorescence

Job description

Zachary Piper Solutions is seeking a Sr Research Associate to support a biotechnology company focused on developing next-generation immune cell therapies through proprietary thymic engineering and pluripotent stem cell technologies. This position is on-site in Cambridge, MA. The Sr Research Associate will execute cell culture, differentiation, molecular biology, and process development activities supporting the advancement of a stem cell-derived cell therapy product from preclinical development toward commercialization. Join a pioneering team working to transform immunology through innovative regenerative medicine and cell engineering approaches.

Responsibilities for the Sr Research Associate include:

• Perform human pluripotent stem cell (hPSC/iPSC) culture, maintenance, differentiation, and characterization experiments to support therapeutic cell development.
• Execute molecular and cellular biology assays including flow cytometry, RT-qPCR, ddPCR, ELISA, immunohistochemistry, and immunofluorescence analysis.
• Support cell engineering and genetic modification studies while evaluating cell differentiation, functionality, and process optimization.
• Analyze experimental data, troubleshoot protocols, contribute to process standardization, and present findings to project teams.
• Maintain laboratory operations, coordinate compliance and safety activities, manage supplies, and assist in training laboratory personnel.

Required Qualifications for theSr Research Associate include:

• 2+ years of experience in pluripotent stem cell biology, regenerative medicine, cell therapy, molecular biology, or a related biotechnology discipline.
• Hands-on experience with human pluripotent stem cell culture and differentiation, RT-qPCR, ddPCR, flow cytometry, ELISA, and related molecular biology techniques.
• Strong analytical, organizational, troubleshooting, communication, and data analysis skills with the ability to work independently and collaboratively in a fast-paced environment.
• Bachelor’s or Master’s degree in Biology, Regenerative Medicine, Molecular Biology, Genetic Engineering, Cell Biology, Biotechnology, or a related scientific field.

Compensation for the Sr Research Associate include:

• Salary Range: $80,000-$100,000 depending on experience
• Full Benefits Package: PTO, Paid Holidays, Medical, Dental, Vision, 401K, Tuition Reimbursement, Sick Leave as required by law

Keywords:

pluripotent stem cells, stem cell biology, iPSC, hPSC, regenerative medicine, cell therapy, thymic engineering, molecular biology, cell engineering, flow cytometry, RT-qPCR, ddPCR, ELISA, immunohistochemistry, immunofluorescence, tissue culture, cell differentiation, biotechnology, preclinical research, Cambridge MA, immunology, genetic engineering, laboratory research, process development, translational science