Sr. Director/Executive Director, Clinical Science, Medical Affairs

Gh Gruppe; United States; Remote; USD 300,000 - 380,000; Full time

Job summary

An innovative biopharmaceutical company is seeking a dynamic Executive Director/Sr. Director in Clinical Science to advance the clinical science in the management of ATTR diseases. This role offers the opportunity to lead impactful initiatives, collaborate with cross-functional teams, and drive scientific excellence in a fast-paced environment. The ideal candidate will have a strong background in cardiovascular diseases, a passion for improving patient lives, and the ability to translate complex clinical needs into actionable strategies. Join a dedicated team committed to transforming patient care through scientific innovation and collaboration.

Benefits

Flexible PTO

Robust Compensation Package

Access to Learning Resources

Rapid Career Advancement

Commitment to Diversity, Equity & Inclusion

Patient Days Engagement

Collaborative Work Environment

Qualifications

• 5+ years in the pharmaceutical industry with a focus on medical affairs.
• Proven track record in developing and executing Phase 4 studies.

Responsibilities

• Develop clinical strategies and optimize plans for post-launch.
• Lead initiatives impacting clinical care and patient engagement.

Skills

Clinical Science

Medical Affairs

Cardiovascular Diseases

Leadership Skills

Communication Skills

Project Management

Regulatory Requirements

Scientific Rigor

Education

Advanced Degree (MD, DO, MBBS)

Job description

Sr. Director/Executive Director, Clinical Science, Medical Affairs

Remote - United States

Eidos Therapeutics, an affiliate of BridgeBio Pharma, is a Phase 3 developmental-stage biopharmaceutical company focused on addressing the large and growing unmet need in diseases caused by transthyretin, or TTR, amyloidosis, or ATTR. We seek to treat this well-defined family of diseases at their collective source by stabilizing TTR. Our investigational product, acoramidis (AG10), is an orally administered small molecule designed to potently stabilize TTR, a potentially best-in-class treatment aiming to halt the progression of ATTR diseases.

BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases and cancers with clear genetic drivers. We bridge the gap between remarkable advancements in genetic science in academic institutions and the delivery of meaningful medicines to patients. Founded in 2015, the company has built a portfolio of 30+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs.

Our focus on scientific excellence and rapid execution aims to translate today’s discoveries into tomorrow’s medicines. We have U.S. offices in San Francisco, Palo Alto, and Raleigh, with small satellites in other parts of the country. We also have international offices in Montreal, Canada, and Zurich, Switzerland, and are expanding across Europe.

To learn more about our story and company culture, visit us at eidostx.com | https://bridgebio.com

The Executive Director/Sr. Director, Clinical Science, Medical Affairs (acoramidis), is responsible for advancing the clinical science in diagnosis, management and monitoring in ATTR-CM and related fields to further the primary goal of the company to support patients.

Responsibilities

• Content ideation, writing or review, or both, for abstracts, manuscripts, ad boards includes ensuring deliverables happen on time through correct process steps
• Protocol ideation and syndication with KOLs, writing or review, or both, for any Med Affairs study, including HEOR; site monitors for all clinical studies; includes ensuring deliverables happen on time through correct process steps
• Review of any clinical material (e.g., SRLs, regulatory documents like PBRERs) that Med Affairs generates or is asked to review
• Supplement customer engagement broadly written (e.g., at congresses, in the field where appropriate, ad boards, steercos), leading certain initiatives (e.g., compendia, global access initiatives) that impact clinical care
• Develop and optimize clinical strategy (with cross-functional collaboration): translate clinical science and insights into post-launch clinically relevant short- and long-term plans (abstracts, manuscripts, studies, registries, etc.)
• Translate unmet clinical needs and clinical implications of diagnostic and treatment dynamics into Medical plans that improve clinical outcomes

No matter your role at BridgeBio, successful team members are:

• Patient Champions, who put patients first and uphold strict ethical standards
• Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset
• Truth Seekers, who are detailed, rational, and humble problem solvers
• Individuals Who Inspire Excellence in themselves and those around them
• High-quality executors, who execute against goals and milestones with quality, precision, and speed

Education, Experience & Skills Requirements

• Advanced degree (MD, DO, MBBS) in medicine required; subspecialization in cardiovascular diseases a plus
• At least 5 years of professional experience with more than 5 years in the pharmaceutical/biotechnology industry and experience in medical affairs (cardiovascular focus highly preferred).
• Proven track record of developing and executing successful Phase 4 studies, including registries and real-world interventional studies
• Ability to apply scientific rigor to understand and debate detailed clinical science aspects of disease areas and approach clinical science discussions with confidence and curiosity, both internally and externally
• Ability to develop advanced clinical content, including protocols (cardiovascular focus strongly preferred)
• Previous experience managing functional budget including vendor relationships.
• Familiarity with and understanding of global regulatory requirements and industry guidelines
• Excellent leadership skills and exceptional communication and interpersonal skills to interact effectively with internal and external stakeholders
• Solid clinical science acumen (cardiovascular focus strongly preferred)
• Ability to work independently and as part of a team in fast-paced environments.
• Ability to manage multiple priorities and meet deadlines
• Commitment to excellence, continuous learning, flexibility, and persistence
• Demonstrated ability to work collaboratively in cross-functional teams and manage multiple projects simultaneously
• And, most importantly, a genuine passion for improving patient lives through scientific innovation

What We Offer

• Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts
• A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
• An unyielding commitment to always putting patients first. Learn more about how we do this here
• A de-centralized model that enables our program teams to focus on advancing science and helping patients. Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science
• A place where you own the vision – both for your program and your own career path
• A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
• Access to learning and development resources to help you get in the best professional shape of your life
• Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
• Flexible PTO
• Rapid career advancement for strong performers
• Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time
• Commitment to Diversity, Equity & Inclusion

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

$300,000 - $380,000 USD

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