Sr./Clinical Trial Manager

Ladders; United States; Remote; USD 180,000 - 195,000; Full time

Benefits offered by this job

Remote work

Travel opportunities

Immunology pipeline

Mentorship program

Dynamic environment

Job summary

Ladders is seeking a Sr./Clinical Trial Manager to drive operational execution across multiple clinical studies in a fast-moving biopharmaceutical environment. You will partner with internal stakeholders, CROs, sites, and vendors to keep start-up, monitoring, and closeout on track from start to finish.

The role requires 10+ years in trial management (7+ years for a Clinical Trial Manager), global study experience, and solid FDA/ICH/GCP knowledge.

Qualifications

• Bachelor's degree in a related field.
• Senior role requires 10+ years in trial management; 7+ for Manager.
• Experience with global immunology or rare disease trials is a plus.
• Strong vendor management and regulatory knowledge (FDA/ICH/GCP).

Responsibilities

• Support development and execution of study operations plans and timelines.
• Oversee vendor activities, performance metrics and issue resolution.
• Maintain trial budgets, track spending and flag financial risks.
• Manage risk and issues logs, driving timely resolutions.
• Coordinate input for protocols and monitoring plans.
• Oversee global start-up, site activation and monitoring.
• Build relationships with sites, CROs and internal stakeholders.

Skills

Clinical trial management

Vendor management

Budget oversight

Global studies

FDA regulations

GCP compliance

Cross-functional collaboration

Communication skills

Problem solving

Detail-oriented

Education

Bachelor's degree

Job description

For our client, we are seeking a Sr./Clinical Trial Manager to join the team of a leader in the Pharmaceuticals & Biotech space.

This role will drive operational execution across clinical studies, with a strong focus on planning, vendor management, financial oversight, and site activation. The person in this position will partner closely with internal stakeholders, CROs, clinical sites, and external vendors to keep studies on track from start-up through monitoring and closeout. This is a highly cross-functional role supporting complex programs in a fast-moving biopharmaceutical environment. Experience with global trials, immunology, or rare disease programs would be especially valuable.

Location: Remote

Compensation: $180,000 – $195,000 annually

Responsibilities

• Support development and execution of detailed study operational plans and timelines
• Oversee vendor activities, including performance metrics and issue resolution
• Maintain clinical trial budgets, track spending, and elevate financial risks
• Manage study risk and issue logs, driving resolution activities
• Coordinate input for clinical documents such as protocols and monitoring plans
• Oversee global study start-up, site activation, and monitoring activities
• Build relationships with clinical sites, CROs, and internal stakeholders

Qualifications

• Bachelor's degree with 10+ years of experience for Sr. Clinical Trial Manager or 7+ years for Clinical Trial Manager
• Experience in trial management within a biopharmaceutical company; startup experience is a plus
• Proven track record in managing complex clinical trials from Phase 1 to Phase 3, with global experience preferred
• Preferred experience in immunology and/or rare disease clinical trials
• Strong background in managing CROs and clinical vendors, including labs and clinical technology
• In-depth knowledge of FDA regulations, ICH guidelines, and Good Clinical Practice
• Excellent communication, organization, and problem-solving skills, with a focus on detail

Benefits

• Remote work flexibility with periodic travel for team events
• Opportunity to contribute to the company's immunology pipeline
• Mentorship opportunities for junior team members
• Engagement in a dynamic and collaborative work environment

Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.