Senior VP, Translational Science: Lead Clinic-Ready Programs

5AM Ventures; Berkeley (CA); On-site; USD 350,000 - 550,000; Full time

Job summary

Renasant Bio in Berkeley is seeking a Senior Vice President, Translational Science to guide programs from late discovery into the clinic. You will lead a translational biology team, shape early clinical strategy, and drive IND enabling work with direct reporting to the Chief Scientific Officer.

You will oversee decisions on dose selection, endpoints, and readouts, while coordinating regulatory interactions and partnerships with CROs.

Qualifications

• Ph.D. or MD/PhD in a relevant scientific discipline.
• 15 years of drug development experience in biotech or pharma, with a proven record as a seasoned drug developer.
• Demonstrated success taking multiple programs or proofs of concept from preclinical development into Phase 1 or Phase 2 studies in patients.
• Has successfully accelerated at least one program to the clinic.
• Deep small molecule drug development experience, including pharmacokinetics, pharmacology, toxicology and the path to IND is required.
• Experience spanning multiple therapeutic areas; renal experience is not required but considered ideal.
• Track record of building, managing and developing teams, and managing external partners such as CROs.
• Strong scientific judgment, with the ability to make clear decisions on incomplete data.
• Excellent communication skills with scientific, executive, Board and investor audiences.

Responsibilities

• Define and lead the translational strategy for developing programs from discovery through Phase 1/2.
• Serve as the translational science voice guiding go/no go decisions across biology, translational and related strategies.
• Own the translational strategy to support bringing molecules from discovery into clinical development.
• Partner with the CSO and CMO on dose selection, endpoints and related readouts.
• Contribute to regulatory strategy and represent the science in pre-IND interactions with FDA and other agencies.
• Lead and develop a highly performing translational science team.
• Communicate program strategy and data clearly to investors, partners and the Board.

Skills

Scientific leadership

Strategic thinking

Cross-functional collaboration

Communication skills

Education

Ph.D. or MD/PhD

Job description

Renasant Bio in Berkeley is seeking a Senior Vice President, Translational Science to guide programs from late discovery into the clinic. You will lead a translational biology team, shape early clinical strategy, and drive IND enabling work with direct reporting to the Chief Scientific Officer.

You will oversee decisions on dose selection, endpoints, and readouts, while coordinating regulatory interactions and partnerships with CROs.