Senior Virology Scientist: Viral Vector & Delivery

Generate:Biomedicines; Somerville (MA); On-site; USD 125,000 - 175,000; Full time

Job summary

Generate:Biomedicines in Somerville seeks a Senior Scientist in Molecular Virology to design and lead research on viral vector and RNA delivery platforms, advancing programs from in vitro evaluation through in vivo validation to support clinical candidate selection.

You will lead experiments, mentor junior scientists, and collaborate with computational and therapeutic experts to interpret data, make decisions, and communicate findings for regulatory readiness.

Qualifications

• PhD in Virology, Molecular Biology, Microbiology, Biochemistry, or closely related life science field.
• 4+ years postdoctoral or industry R&D experience with independent virology research.
• Hands-on mammalian cell culture, viral propagation, reverse genetics, cloning, site-directed mutagenesis, and recombinant vector design.
• Experience with qPCR, ddPCR, ELISA, flow cytometry, Western blotting, and transfection methods.
• Experience with NGS library prep, CRISPR screening, and basic sequence/data analysis tools.
• Experience applying agentic platforms and protein design tools.
• Proficiency with electronic lab notebooks (ELN) and LIMS.
• Strong project management, problem-solving, and cross-disciplinary communication.

Responsibilities

• Lead molecular virology research; design, execute, and oversee cancer virology and mammalian cell culture experiments in vitro and in vivo.
• Develop and optimize high-throughput screening assays using qPCR, ddPCR, flow cytometry, Western blotting, and sequencing.
• Analyze complex datasets, interpret results, and recommend next steps toward clinical candidate selection.
• Collaborate with computational scientists and therapeutic experts to evaluate delivery platforms.
• Maintain accurate, complete lab records and prepare reports and manuscripts for regulatory filings.
• Provide day-to-day scientific guidance to researchers and mentor junior scientists.
• Set clear research goals, track progress, and communicate findings and challenges to cross-functional partners.
• Ensure biosafety and regulatory compliance across all activities.

Skills

Scientific leadership

Project management

Data interpretation

Written & verbal communication

Cross-functional collaboration

Mentoring

Education

PhD in Virology or related life science

Tools

qPCR/ddPCR

Flow cytometry

Western blotting

NGS library prep

CRISPR screening

ELN

LIMS

Viral propagation

Mammalian cell culture

Molecular cloning

Reverse genetics

Job description

Generate:Biomedicines in Somerville seeks a Senior Scientist in Molecular Virology to design and lead research on viral vector and RNA delivery platforms, advancing programs from in vitro evaluation through in vivo validation to support clinical candidate selection.

You will lead experiments, mentor junior scientists, and collaborate with computational and therapeutic experts to interpret data, make decisions, and communicate findings for regulatory readiness.