Senior Technician Operations, 2nd Shift

Merck; Durham (NC); On-site; USD 64,000 - 100,000; Full time

Benefits offered by this job

Annual bonus

Long-term incentive

Medical, dental, vision benefits

Job summary

Merck in Durham, NC is seeking a Senior Technician, Operations for second shift (2:00pm-10:30pm) to support Drug Substance operations. You will perform aseptic gowning, operate and troubleshoot equipment, maintain records, and contribute to continuous improvement.

Requires GMP manufacturing experience or life science/engineering degree, strong communication, ability to lift 50 lbs, and familiarity with GDP/GMP practices. Eligible for annual bonus and long-term incentive; comprehensive benefits.

Qualifications

• At least two (2) years of GMP manufacturing/processing experience, or a Bachelor’s degree in Life Science or Engineering.
• Demonstrated written and verbal communications skills.
• Must pass aseptic gowning qualifications (full coverage apparel).
• Computer literacy including browsers, email, spreadsheets, and word processing.
• Able to lift 50 lbs, bend, stoop, squat, crawl, climb ladders, and wear a respirator.

Responsibilities

• Support production team as operations expert on the shop floor.
• Create, review, and edit batch records, SOPs, job aides, training, and engineering documents.
• Identify and address compliance, environmental, safety, and process deviations with appropriate personnel.
• Participate in team meetings, kaizen events, and other operations/quality initiatives.
• Maintain equipment/process knowledge and detailed records.

Skills

GMP manufacturing experience

Written and verbal communication

Aseptic gowning qualification

Computer literacy

Lift 50 lbs and PPE use

Education

High School Diploma/GED

Tools

MES

SAP

DeltaV

Job description

Senior Technician, Operations

Our Manufacturing Operations teams are the people that make therapies for our patients. We work in the manufacturing plants with a “Safety First, Quality Always” mindset, striving for continuous improvement, and earn our right to produce. We work in local plants connected to our global manufacturing network supplying the highest quality of raw materials, intermediates, and finished products.

Job Description

Our Manufacturing Operations teams are the people that make therapies for our patients. We work in the manufacturing plants with a “Safety First, Quality Always” mindset, striving for continuous improvement, and earn our right to produce. We work in local plants connected to our global manufacturing network supplying the highest quality of raw materials, intermediates, and finished products.

Production Support

• Supports production team as operations expert through shop floor manufacturing.
• Author, review, and/or edit operations and technical documentation (Batch Records, SOPs, Job Aides, training, and engineering documents) to support project and future operations.
• Identifies and addresses compliance, environmental, safety, and process deviations as appropriate while coordinating with appropriate personnel.
• Actively participate in team meetings, waste walkthroughs, 5S, kaizen events, or any other operations, lean six-sigma, quality, safety or environmental training/initiatives as required.

Operational Expertise

• Competent execution and ownership to meet production targets for area within responsibility including:
• Attending and escalation of concerns or needs at daily huddles and as needed
• Cleaning, setup, operation and troubleshooting of equipment and facilities
• Maintenance and transportation of consumable and material inventories
• Maintenance of excellent recordkeeping and housekeeping
• Drives culture of continuous improvement. Implements and raises ideas to increase success of group
• Participates on and/or performs activities to support technical functions such as Kaizen events, ad-hoc sampling, or protocol execution.
• Maintains detailed knowledge of equipment and processes.
• Identifies and addresses compliance, environmental, safety, and process deviations as appropriate while notifying appropriate personnel.

Education Minimum Requirement

• High School Diploma/GED or higher

Required Experience And Skills

• At least two (2) years of GMP manufacturing/processing experience, or a Bachelor’s degree in Life Science or Engineering
• Demonstrated written and verbal communications skills
• Must be able to successfully pass and maintain aseptic gowning qualifications. Aseptic gowning requires that all skin and hair be covered through wearing the following: beard/mustache cover, hair net, hood and facemask, goggles, jumpsuit, gloves, and boots.
• Computer literacy (internet browsers, e-mail, spreadsheets, word processing)
• Must be willing and able to lift 50 lbs, bend, stoop, squat, crawl, twist, climb ladders, and wear a respirator
• This position is for second shift, Mon-Fri (2:00pm-10:30pm).
• Successful completion of TB titer and Chest X-ray are required.

Preferred Experience And Skills (General)

• Minimum Associates Degree in science or related field
• Bioworks Certificate (working in an FDA or similar regulated industry)
• Applicable mechanical and project management experience
• Experience with automated systems (MES, SAP, DeltaV, or similar)
• Experience with on-the-floor cGMP manufacturing and familiarity with regulatory requirements and Good Documentation Practices (GDP)
• Demonstrated ability to work both independently and as a part of a team

Senior Technician supporting Drug Substance operations

• Aseptic Behaviors
• Aseptic Techniques & Manipulations
• Pipetting
• Weigh and Dispense
• Media Make up and Dispense

Salary Range For This Role Is

$63,800 - $100,400

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.

Required Skills

Biopharmaceutical Manufacturing, Biopharmaceutical Manufacturing, Business Process Management (BPM), CNC Operations, Computer Literacy, Data Analysis, FDA Regulations, Global Manufacturing, GMP Compliance, Good Manufacturing Practices (GMP), Laboratory Techniques, Life Science, Manufacturing Compliance, Manufacturing Quality Control, Master Batch Records, Material Selection, Oral Communications, Pharmaceutical Process Development, Production Operations, Production Planning, Raw Materials, Regulatory Compliance, SAP PP (Production Planning), Shift Work, Shop Floor Management {+ 2 more}

Preferred Skills

US And Puerto Rico Residents Only

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

San Francisco Residents Only

We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance.

Los Angeles Residents Only

We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance.

Employee Status

Regular

Relocation

No relocation

VISA Sponsorship

No

Travel Requirements

10%

Flexible Work Arrangements

Not Applicable

Shift

2nd - Evening

Valid Driving License

No

Hazardous Material(s)

Cleaning Supplies

Job Posting End Date

08/21/2026

• A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID

R410044