Senior Technician Operations, 2nd Shift

NCBiotech; Durham (NC); On-site; USD 64,000 - 100,000; Full time

Benefits offered by this job

Medical, Dental, Vision Benefits

401(k) Plan

Paid Holidays & Vacation

Job summary

Merck & Co., Inc. is seeking a Senior Technician to support Drug Substance operations on the 2nd shift (2:00pm-10:30pm). The role involves shop floor manufacturing, equipment setup, and continuous improvement activities within a GMP environment.

Responsibilities include preparing and reviewing batch records, SOPs, and training materials, while ensuring compliance with regulatory requirements and corporate quality standards. Strong communication and physical readiness are essential.

Qualifications

• Minimum two years GMP manufacturing/processing experience or a Bachelor’s degree in Life Science/Engineering.
• Demonstrated written and verbal communications skills.
• Must pass aseptic gowning qualifications and wear required PPE.
• Proficient computer skills (email, spreadsheets, word processing).
• Able to lift 50 lbs and perform physical tasks including climbing ladders.

Responsibilities

• Support production as operations expert on the shop floor.
• Create or edit operations and technical documentation (Batch Records, SOPs, training materials).
• Address compliance, environmental, safety, and process deviations in coordination with team.

Skills

Biopharmaceutical Manufacturing

Data Analysis

Regulatory Compliance

GMP Knowledge

Computer Literacy

Education

High School Diploma/GED or higher

Tools

SAP PP

MES

DeltaV

Job description

Senior Technician, Operations

Our Manufacturing Operations teams are the people that make therapies for our patients. We work in the manufacturing plants with a “Safety First, Quality Always” mindset, striving for continuous improvement, and earn our right to produce. We work in local plants connected to our global manufacturing network supplying the highest quality of raw materials, intermediates, and finished products.

Responsibilities may include but are not limited to:

Production Support

• Supports production team as operations expert through shop floor manufacturing.
• Author, review, and/or edit operations and technical documentation (Batch Records, SOPs, Job Aides, training, and engineering documents) to support project and future operations.
• Identifies and addresses compliance, environmental, safety, and process deviations as appropriate while coordinating with appropriate personnel.
• Actively participate in team meetings, waste walkthroughs, 5S, kaizen events, or any other operations, lean six-sigma, quality, safety or environmental training/initiatives as required.

Operational Expertise

• Competent execution and ownership to meet production targets for area within responsibility including:
  • Attending and escalation of concerns or needs at daily huddles and as needed
  • Cleaning, setup, operation and troubleshooting of equipment and facilities
  • Maintenance and transportation of consumable and material inventories
  • Maintenance of excellent recordkeeping and housekeeping
• Drives culture of continuous improvement. Implements and raises ideas to increase success of group
• Participates on and/or performs activities to support technical functions such as Kaizen events, ad-hoc sampling, or protocol execution.
• Maintains detailed knowledge of equipment and processes.
• Identifies and addresses compliance, environmental, safety, and process deviations as appropriate while notifying appropriate personnel.

Education Minimum Requirement:

• High School Diploma/GED or higher

Required Experience and Skills:

• At least two (2) years of GMP manufacturing/processing experience, or a Bachelor’s degree in Life Science or Engineering
• Demonstrated written and verbal communications skills
• Must be able to successfully pass and maintain aseptic gowning qualifications. Aseptic gowning requires that all skin and hair be covered through wearing the following: beard/mustache cover, hair net, hood and facemask, goggles, jumpsuit, gloves, and boots.
• Computer literacy (internet browsers, e‑mail, spreadsheets, word processing)
• Must be willing and able to lift 50 lbs, bend, stoop, squat, crawl, twist, climb ladders, and wear a respirator
• This position is for second shift, Mon-Fri (2:00pm-10:30pm).
• Successful completion of TB titer and Chest X‑ray are required.

Preferred Experience and Skills (General):

• Minimum Associates Degree in science or related field
• Bioworks Certificate (working in an FDA or similar regulated industry)
• Applicable mechanical and project management experience
• Experience with automated systems (MES, SAP, DeltaV, or similar)
• Experience with on-the-floor cGMP manufacturing and familiarity with regulatory requirements and Good Documentation Practices (GDP)
• Demonstrated ability to work both independently and as a part of a team

The following experience is a significant advantage for a Senior Technician supporting Drug Substance operations:

• Aseptic Behaviors
• Aseptic Techniques & Manipulations
• Pipetting
• Weigh and Dispense
• Media Make up and Dispense

The salary range for this role is:

$63,800 - $100,400

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.

Required Skills:

Biopharmaceutical Manufacturing, Biopharmaceutical Manufacturing, Business Process Management (BPM), CNC Operations, Computer Literacy, Data Analysis, FDA Regulations, Global Manufacturing, GMP Compliance, Good Manufacturing Practices (GMP), Laboratory Techniques, Life Science, Manufacturing Compliance, Manufacturing Quality Control, Master Batch Records, Material Selection, Oral Communications, Pharmaceutical Process Development, Production Operations, Production Planning, Raw Materials, Regulatory Compliance, SAP PP (Production Planning), Shift Work, Shop Floor Management {+ 2 more}

Preferred Skills:

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status: Regular

Relocation: No relocation

VISA Sponsorship: No

Travel Requirements: 10%

Flexible Work Arrangements: Not Applicable

Shift: 2nd - Evening

Valid Driving License: No

Hazardous Material(s): Cleaning Supplies

Job Posting End Date: 08/21/2026