Senior Systems Engineer - Automation for Oncology Diagnostics

Spencer Rigby Ltd.; California; On-site; USD 150,000 - 190,000; Full time

Job summary

Spencer Rigby Ltd. in California partners with a rapid-growth molecular diagnostics company to build a senior systems engineer role that bridges assay development and automation.

The candidate will convert bench protocols into scalable, reliable production processes on an automated platform, own labware qualification, and drive verification studies while aligning with FDA requirements and production timelines.

Qualifications

• Experience scaling lab protocols to automated production.
• Familiarity with FDA design controls and validation.
• Experience with verification and validation studies.
• Knowledge of library preparation workflows in NGS.

Responsibilities

• Convert bench protocols into reliable production-ready processes for automation.
• Qualify labware, set operating margins, and run FMEA to ensure dependable steps.
• Lead sequencing automation within the oncology workflow end-to-end.
• Evaluate new sequencing instruments and onboard vendor partnerships.
• Plan verification/validation studies as workflows transition to production.
• Coordinate with Regulatory/Quality for proper validation and documentation.

Skills

Lab automation

Process scaling

Systems integration

NGS sequencing

Regulatory knowledge

Design of experiments

Tools

Hamilton STAR/STAR2

VENUS programming

Illumina sequencing

Oxford Nanopore sequencing

Job description

Spencer Rigby Ltd. in California partners with a rapid-growth molecular diagnostics company to build a senior systems engineer role that bridges assay development and automation.

The candidate will convert bench protocols into scalable, reliable production processes on an automated platform, own labware qualification, and drive verification studies while aligning with FDA requirements and production timelines.