Senior Staff High Throughput Product Technical Lead

Illumina; San Diego (CA); On-site; USD 156,000 - 233,000; Full time

Benefits offered by this job

Health benefits

Retirement benefits

Paid time off

Equity or bonus programs

Job summary

Illumina is seeking a Senior Staff High Throughput Product Technical Lead to drive platform health and lifecycle strategy for our sequencing platforms. This role coordinates across R&D, Quality, Operations, Service, Supply Chain, Marketing, and Commercial teams to translate insights into investments and improvements.

The ideal candidate combines deep technical leadership with strong influence, systems thinking, and decision-making skills, capable of leading complex initiatives in a matrixed

Qualifications

• Strong systems-level understanding of integrated product ecosystems (hardware, consumables, software, service, operations).
• Experience driving product quality, reliability, lifecycle management, or post-market sustainment initiatives.
• Ability to influence senior leaders and align diverse stakeholders around priorities.
• Understanding of quality systems, risk management, and regulated product development environments.
• Experience translating technical issues and field data into strategic investments.
• Proven track record leading complex product/platform strategies in a matrixed environment.

Responsibilities

• Serve as the technical and strategic lead for assigned high-throughput platforms, driving platform health and lifecycle strategy.
• Develop an integrated view of platform performance across quality, reliability, serviceability, customer experience, and business outcomes.
• Translate feedback, field insights, operational data, and performance trends into prioritized improvements.
• Lead cross-functional efforts to identify and resolve systemic product issues and platform risks.
• Assess impacts of product and process changes to ensure balanced decisions.
• Drive lifecycle planning including enhancements, service strategies, cost optimization, obsolescence, and end-of-support planning.
• Partner with Quality and Regulatory teams for post-market surveillance and risk management.
• Lead On-Market Core Teams and forums to drive alignment and execution.
• Communicate platform health, risk, and investment recommendations to senior leadership.
• Influence cross-functional teams to improve product quality, reliability, and lifecycle value.
• Integrate on-market learnings into future platform designs and roadmaps.

Skills

Systems thinking

Executive communication

Stakeholder management

Cross-functional leadership

Education

Bachelor’s degree

Master’s degree

PhD with experience

Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Exciting opportunity to serve as the technical leader for Illumina's high-throughput sequencing platforms. The Senior Staff Product Technical Lead is responsible for driving platform health, lifecycle strategy, and cross-functional alignment to deliver exceptional customer experience, product quality, reliability, and business performance.

The Technical Lead serves as the primary integration point across R&D, Quality, Operations, Service, Supply Chain, Marketing, and Commercial organizations, translating customer, field, and operational insights into prioritized platform investments and improvement opportunities. This role identifies and mitigates platform risks, guides lifecycle decisions, and ensures on-market learnings inform future product designs, roadmaps, and business strategies.

Operating in a highly matrixed environment, the ideal candidate is a strong technical leader with exceptional influence, systems thinking, and decision-making skills. The candidate must independently lead complex initiatives, align diverse stakeholders, balance technical and business tradeoffs, and drive measurable improvements in platform performance throughout the product lifecycle.

Responsibilities

• Serve as the technical and strategic lead for assigned high-throughput platforms, driving platform health, performance, and lifecycle strategy.
• Develop and maintain an integrated view of platform performance across quality, reliability, serviceability, customer experience, and business outcomes.
• Translate customer feedback, field insights, operational data, and product performance trends into prioritized improvement opportunities.
• Lead cross-functional efforts to identify, prioritize, and resolve systemic product issues and emerging platform risks.
• Assess customer, technical, operational, and business impacts of product and process changes, ensuring balanced decision-making.
• Drive lifecycle planning, including product enhancements, service strategies, cost optimization, obsolescence management, and end-of-support planning.
• Partner with Quality and Regulatory teams to support post-market surveillance, risk management, compliance, and field action activities.
• Lead On-Market Core Teams (OMCTs) and platform decision forums to drive alignment, accountability, and execution.
• Communicate platform health assessments, risk profiles, strategic priorities, and investment recommendations to senior leadership.
• Influence cross-functional teams to deliver measurable improvements in product quality, reliability, customer experience, and lifecycle value.
• Partner with development teams to ensure on-market learnings are incorporated into future platform designs and roadmap decisions.

Experience\Knowledge Requirements

• Strong systems-level understanding of integrated product ecosystems, including hardware, consumables, software, service, and operational workflows.
• Experience driving product quality, reliability, lifecycle management, or post-market sustainment initiatives.
• Demonstrated ability to influence senior leaders and align technical, operational, and commercial stakeholders around strategic priorities.
• Strong understanding of quality systems, risk management frameworks, and regulated product development environments.
• Experience translating technical issues, customer insights, and field data into strategic business decisions and investment recommendations.
• Proven experience leading complex product, platform, or portfolio strategies in a highly matrixed environment.
• Excellent communication, executive presentation, and stakeholder management skills.
• Working knowledge of manufacturing, supply chain, field service, customer support, and commercial operations.
• Experience with next-generation sequencing products and platforms strongly preferred.
• Familiarity with FDA-regulated product development processes, design controls, and post-market requirements.

Education Requirements

• Typically requires a minimum of 12 years of related experience with a Bachelor’s degree; or 8 years and a Master’s degree; or a PhD with 5 years of experience; or equivalent experience.

The estimated base salary range for the Senior Staff High Throughput Product Technical Lead role based in the United States of America is: $155,600 - $233,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long-term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [e-mail]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.