Sr. Staff Product Manager (HT/NGS)

Illumina; San Diego (CA); On-site; USD 156,000 - 233,000; Full time

Benefits offered by this job

Genomics sequencing access

Health/dental/vision benefits

Retirement benefits

Paid time off

Job summary

Illumina seeks a Sr. Staff Product Manager to lead platform-level development and launch execution for sequencing systems. You will drive end-to-end workflow solutions, align R&D, operations and Commercial teams, and champion market-driven product requirements.

The ideal candidate brings extensive experience in next-gen sequencing, proven PM leadership, and a track record of successful capital equipment launches, with strong public speaking and strategic thinking abilities.

Qualifications

• Experience with next-generation sequencing technologies (SBS, etc.).
• Proven product management experience across the full product development lifecycle for a major product line.
• Track record of successful commercial launches of new products.
• Strong public speaking and executive-level presentation skills.
• Experience developing system requirements with both hardware and software inputs.
• Ability to translate market needs into design inputs through data-driven decisions.

Responsibilities

• Act as primary PM for novel system-level product development across end-to-end workflow.
• Collaborate with R&D, Operations, Commercial to ensure end-to-end system delivery.
• Define product requirements based on customer/market needs and business goals.
• Serve as product champion within cross-functional teams and guide early-phase to post-launch decisions.
• Develop business cases and sales forecasts for new product requirements and pricing.
• Partner with Commercial teams to establish go-to-market and launch strategies.
• Create launch collateral with Product Marketing and support market development efforts.

Skills

Next-generation sequencing

Cross-functional leadership

Product management

Data-driven decision making

Public speaking

Commercial launches

Education

Bachelor’s degree or higher

Tools

Hardware & software development

Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

We are seeking a Product Manager with deep expertise in next-generation sequencing, and a proven track record of successful commercial capital equipment launches. This role will lead product management at the platform-level product development and launch execution, ensuring end-to-end and configurable solutions that integrate seamlessly across both on-market and in-development products. The ideal candidate will be a strategic thinker, with both commercial and technical expertise, strong cross-functional leadership skills, capable of driving decisions that balance R&D innovation with commercial success.

Tasks and Responsibilities

Act as primary product manager in a novel product development at the system level (being able to cover whole end to end workflow solutions for main use cases for the platform).
Collaborate deeply with R&D, Operations, Commercial, and cross-functional teams to ensure end-to-end system delivery and compatibility with both on-market and future products.
Establish product/system level requirements as defined by customer/market and business need, leveraging best practices and data driven decision making including market research, voice of customer, business analytics, customer use cases etc.
Serve as product and customer champion within a cross-functional core team, acting as a strong cross functional partner to effectively support product development in both early-phase and post-launch decisions.
Develop business cases to support key decision making for new product requirements, pricing and establish initial sales forecast predictions.
Partner with key commercial stakeholders to establish commercialization strategies and approaches to ensure product launch success.
Serve as product expert in partnership with Product Marketing to develop product launch value proposition, messaging, product training and launch collateral (including market development studies, presentations, publications and general literature to support the product).
Partner with key product management and regional marketing stakeholders to define key growth areas for application enablement and market expansion and recommended strategies to unlock growth through product development, sales enablement tools and market development efforts.
Understand key business drivers, based on data and analytics, market trends and direct interaction with Commercial teams and customers.
Build close relationships with key customers, thought leaders, partners, and industry influencers to stay abreast of emerging market trends, be able to communicate those emerging trends actively to the internal team to adjust product placement and features as needed.
Establish strong cross functional partnerships with Research, Product Development, Operations, Quality, Commercial and Global Marketing.

Preferred Experience

Typically requires a minimum of 12 years of related experience with a Bachelor’s degree; or 8 years and a Master’s degree; or a PhD with 5 years of experience; or equivalent experience. Must have experience in next generation sequencing technologies such as SBS and others. Real world experience showing customer implementation of sequencing workflows a plus. Must have demonstrated product management experience throughout the product development process, for a major product line – capital equipment preferred. Must have demonstrated track record of effective public speaking skills and executive level presentation experience. Must have demonstrated successful commercial launch of a new product (in an active role; not support role). Must have experience in developing system requirements, experience with both hardware and software is desirable. Must have demonstrated experience working on early-development products, working heavily with R&D teams to guide product-market fit and translation of product requirements into design inputs. Must have experience in developing product strategy and product roadmaps in a collaborative environment. Prior experience in market development is highly desired. Must have strong analytical skills – ability to tie detailed analysis to larger strategy and make data driven decisions is critical.

Estimated Base Salary

The estimated base salary range for the Sr. Staff Product Manager (HT/NGS) role based in the United States of America is: $155,600 - $233,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package.

Benefits

We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

Culture & Inclusion

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility.

Equal Opportunity Employer

We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Background Check

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws.

Artificial Intelligence Policy

Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process.

Accommodation & Contact

If you require accommodation to complete the application or interview process, please contact [e-mail].

Information About the Posting

The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.

About Illumina & Rewards

The potential of genomics to change the world is unparalleled. At Illumina, we are leading the way. Our technology empowers researchers and clinicians globally to improve cancer treatments, change the course of diseases, protect the environment, and fight food insecurity. We are made up of dedicated professionals, all-in on creating a better world – and we need every skill set on our path to making genomics useful for all.

Learn more about life at Illumina.

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