Senior Staff High Throughput Product Technical Lead

US01 Illumina, Inc.; San Diego (CA); On-site; USD 156,000 - 233,000; Full time

Benefits offered by this job

Health and retirement benefits

Comprehensive health/dental/vision

Paid time off

Job summary

Illumina, Inc. seeks a Senior Staff High Throughput Product Technical Lead to drive platform health, lifecycle strategy, and cross‑functional alignment across R&D, Quality, Operations, Service, and Commercial teams.

You will translate customer and field insights into prioritized investments, mitigating risks and guiding product roadmaps. The role requires leading complex initiatives, influencing senior stakeholders, and delivering measurable improvements in platform performance and customer

Qualifications

• Strong systems-level understanding of integrated product ecosystems (hardware, consumables, software, service).
• Experience in quality systems, risk management, and regulated product development environments.
• Excellent communication and stakeholder management; ability to influence senior leaders.

Responsibilities

• Serve as technical and strategic lead for assigned high-throughput platforms, driving health and lifecycle strategy.
• Develop integrated view of platform performance across quality, reliability, service, and customer outcomes.
• Translate feedback and field data into prioritized improvement opportunities.
• Lead cross-functional efforts to identify, prioritize, and resolve platform risks.
• Drive lifecycle planning including product enhancements and end-of-support planning.
• Partner with Quality and Regulatory teams to support post-market surveillance and compliance.

Skills

Systems thinking

Leadership

Cross-functional alignment

Quality systems knowledge

Regulatory knowledge (FDA)

Communication skills

Executive presentation

High-throughput sequencing domain

Education

Bachelor's degree or higher

Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Exciting opportunity to serve as the technical leader for Illumina's high-throughput sequencing platforms. The Senior Staff Product Technical Lead is responsible for driving platform health, lifecycle strategy, and cross-functional alignment to deliver exceptional customer experience, product quality, reliability, and business performance. The Technical Lead serves as the primary integration point across R&D, Quality, Operations, Service, Supply Chain, Marketing, and Commercial organizations, translating customer, field, and operational insights into prioritized platform investments and improvement opportunities. This role identifies and mitigates platform risks, guides lifecycle decisions, and ensures on-market learnings inform future product designs, roadmaps, and business strategies.

Operating in a highly matrixed environment, the ideal candidate is a strong technical leader with exceptional influence, systems thinking, and decision-making skills. The candidate must independently lead complex initiatives, align diverse stakeholders, balance technical and business tradeoffs, and drive measurable improvements in platform performance throughout the product lifecycle.

• Serve as the technical and strategic lead for assigned high-throughput platforms, driving platform health, performance, and lifecycle strategy.
• Develop and maintain an integrated view of platform performance across quality, reliability, serviceability, customer experience, and business outcomes.
• Translate customer feedback, field insights, operational data, and product performance trends into prioritized improvement opportunities.
• Lead cross-functional efforts to identify, prioritize, and resolve systemic product issues and emerging platform risks.
• Assess customer, technical, operational, and business impacts of product and process changes, ensuring balanced decision‑making.
• Drive lifecycle planning, including product enhancements, service strategies, cost optimization, obsolescence management, and end‑of‑support planning.
• Partner with Quality and Regulatory teams to support post‑market surveillance, risk management, compliance, and field action activities.
• Lead On‑Market Core Teams (OMCTs) and platform decision forums to drive alignment, accountability, and execution.
• Communicate platform health assessments, risk profiles, strategic priorities, and investment recommendations to senior leadership.
• Influence cross‑functional teams to deliver measurable improvements in product quality, reliability, customer experience, and lifecycle value.
• Partner with development teams to ensure on‑market learnings are incorporated into future platform designs and roadmap decisions.

• Strong systems-level understanding of integrated product ecosystems, including hardware, consumables, software, service, and operational workflows.
• Experience driving product quality, reliability, lifecycle management, or post‑market sustainment initiatives.
• Demonstrated ability to influence senior leaders and align technical, operational, and commercial stakeholders around strategic priorities.
• Strong understanding of quality systems, risk management frameworks, and regulated product development environments.
• Experience translating technical issues, customer insights, and field data into strategic business decisions and investment recommendations.
• Proven experience leading complex product, platform, or portfolio strategies in a highly matrixed environment.
• Excellent communication, executive presentation, and stakeholder management skills.
• Working knowledge of manufacturing, supply chain, field service, customer support, and commercial operations.
• Experience with next-generation sequencing products and platforms strongly preferred.
• Familiarity with FDA-regulated product development processes, design controls, and post‑market requirements.

Education Requirements Typically requires a minimum of 12 years of related experience with a Bachelor’s degree; or 8 years and a Master’s degree; or a PhD with 5 years of experience; or equivalent experience.

The estimated base salary range for the Senior Staff High Throughput Product Technical Lead role based in the United States of America is: $155,600 - $233,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package.

• We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics.

We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility.

We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws.

Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process.

If you require accommodation to complete the application or interview process, please contact [e-mail].

To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf.

The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.

This role is not eligible for visa sponsorship.