Senior Spatial Biomarker Scientist

Bristol Myers Squibb

Seattle (WA)

Hybrid

USD 136,000 - 165,000

Full time

3 days ago
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Job summary

Bristol Myers Squibb seeks a Senior Scientist, Spatial Assays in Seattle to lead the design, validation, and optimization of tissue-based biomarker assays across translational and clinical programs. The role requires expertise in IHC, ISH, multiplex immunofluorescence, and advanced image analysis, with a focus on robust data generation for decision-making.

The candidate will partner with internal labs and external CROs, drive assay transfer, and oversee project timelines and budgets in a

Qualifications

  • Bachelor’s Degree in Life Sciences or related field.
  • Advanced degree (Master’s/PhD) preferred with relevant experience.
  • Experience in tissue-based biomarker assays for translational/clinical studies.

Responsibilities

  • Lead strategy, design, development, and validation of tissue-based biomarker assays (IHC/ISH/mIF).
  • Oversee assay transfer to external labs (CROs) and lifecycle management.
  • Define assay performance criteria and quality control workflows.
  • Collaborate with translational scientists to align assays with hypotheses and endpoints.
  • Manage external collaborations, vendor selection, budgets, and timelines.
  • Develop and implement innovative spatial/digital pathology technologies.
  • Interpret validation data and communicate findings to teams and governance boards.
  • Drive cross-functional projects and ensure data quality for decision-making.
  • Support portfolio-wide standardization and best practices.

Skills

IHC
ISH
mIF
spatial biology
digital pathology
assay validation
CRO management
image analysis
data interpretation
project management

Education

Bachelor’s Degree
Master’s Degree
Ph.D. in Life Sciences

Tools

CosMx
COMET
GeoMx
RNAscope
Akoya
10x Genomics

Job description

Bristol Myers Squibb seeks a Senior Scientist, Spatial Assays in Seattle to lead the design, validation, and optimization of tissue-based biomarker assays across translational and clinical programs. The role requires expertise in IHC, ISH, multiplex immunofluorescence, and advanced image analysis, with a focus on robust data generation for decision-making.

The candidate will partner with internal labs and external CROs, drive assay transfer, and oversee project timelines and budgets in a

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