Senior Scientist, Tissue-Targeted Oligonucleotide Delivery

Alnylam Pharmaceuticals

Cambridge (MA)

On-site

USD 126,000 - 190,000

Full time

14 days+
Application generator

Don’t send a generic resume — generate a resume and cover letter tailored to this exact role.

Get past ATS filters

Job summary

Alnylam Pharmaceuticals in Cambridge, MA, seeks a Sr. Scientist in Delivery Biology to advance targeted delivery strategies for oligonucleotides. The role focuses on discovering delivery solutions across tissues with therapeutic targets in clinical development.

It requires collaboration with chemistry, core delivery technology, and targets teams to drive programs forward. The successful candidate will lead in vitro and ex vivo assays, mentor junior scientists, and operate in a lab-based setting

Qualifications

  • PhD required in a relevant life sciences field.
  • 2–3 years of experience in biopharma setting.
  • Expertise in tissue/cell biology for delivery.
  • Experience with nucleic acids or antibody drug conjugates is a plus.

Responsibilities

  • Develop assays and strategies to enable tissue-specific delivery of oligonucleotide conjugates.
  • Design and interpret in vitro and ex vivo assays to evaluate delivery and outcomes.
  • Collaborate with cross-functional teams to expand delivery into new cell types and tissues.
  • Communicate data, conclusions, and rationale to the team and leadership.
  • Mentor and support the scientific development of junior staff.

Skills

Delivery biology
Oligonucleotide conjugates
Tissue/cell delivery
Collaborative work

Education

PhD in related field

Job description

Alnylam Pharmaceuticals in Cambridge, MA, seeks a Sr. Scientist in Delivery Biology to advance targeted delivery strategies for oligonucleotides. The role focuses on discovering delivery solutions across tissues with therapeutic targets in clinical development.

It requires collaboration with chemistry, core delivery technology, and targets teams to drive programs forward. The successful candidate will lead in vitro and ex vivo assays, mentor junior scientists, and operate in a lab-based setting

Get your free, confidential resume review.
or drag and drop your file here.
Similar jobs

Similar jobs worth comparing

Lead Scientist, Targeted Delivery Biology – Tissue
Lead Scientist, Targeted Delivery Biology – Tissue

Alnylam Pharmaceuticals, Inc. • United States

On-site
USD 126,000 - 190,000
Senior Scientist, Delivery Biology-Tissue Lead
Senior Scientist, Delivery Biology-Tissue Lead

Alnylam Pharmaceuticals • Cambridge (MA)

On-site
USD 126,000 - 190,000
Senior Scientist, Delivery Biology-Tissue Lead
Senior Scientist, Delivery Biology-Tissue Lead

Alnylam Pharmaceuticals, Inc. • United States

On-site
USD 126,000 - 190,000
Associate Scientist II - Delivery Biology & Cell Assays
Associate Scientist II - Delivery Biology & Cell Assays

Alnylam Pharmaceuticals, Inc. • Cambridge (MA)

On-site
USD 68,000 - 101,000
Medical, dental, and vision coverage
401(k) with generous company match
Paid time off
+1
Senior Scientist, Ligand Discovery & Delivery Technologies
Senior Scientist, Ligand Discovery & Delivery Technologies

Alnylam Pharmaceuticals, Inc. • United States

On-site
USD 80,000 - 120,000
Medical, dental, and vision coverage
Life and disability insurance
401(k) with company match
+2
Translational Physician-Scientist Lead - Target & Biomarkers
Translational Physician-Scientist Lead - Target & Biomarkers

Alnylam Pharmaceuticals, Inc. • United States

On-site
USD 202,000 - 274,000
Medical, dental, and vision coverage
Life and disability insurance
401(k) with generous match
Senior Associate Scientist, Delivery Technology
Senior Associate Scientist, Delivery Technology

Alnylam Pharmaceuticals • Cambridge (MA)

On-site
USD 80,000 - 120,000
Comprehensive benefits package
Onsite lab-based role
Associate Scientist II, Delivery Biology
Associate Scientist II, Delivery Biology

Alnylam Pharmaceuticals, Inc. • Cambridge (MA)

On-site
USD 68,000 - 101,000
Medical, dental, and vision coverage
401(k) with generous company match
Paid time off
+1
Senior/Principal Synthetic Chemist - Oligonucleotide Delivery
Senior/Principal Synthetic Chemist - Oligonucleotide Delivery

Autonomous Therapeutics • Oregon (WI)

On-site
USD 120,000 - 180,000
Senior Associate Scientist, Delivery Technology
Senior Associate Scientist, Delivery Technology

Alnylam Pharmaceuticals, Inc. • United States

On-site
USD 80,000 - 120,000
Medical, dental, and vision coverage
Life and disability insurance
401(k) with company match
+2