Senior Scientist - Synthetic Chemistry & Bioconjugation

Autonomous Therapeutics, Inc.; Rockville (MD); Presencial; USD 100.000 - 180.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Equity

Health, dental, and vision insurance

401(k) with company match

Descripción de la vacante

Autonomous Therapeutics, Inc. is seeking a Senior/Principal Scientist in Rockville, MD, to drive the design and synthesis of next-generation oligonucleotide medicines.

You will develop delivery-conjugation strategies and work closely with formulation, biology, and in vivo teams to translate chemistry into therapeutic candidates. The role offers high scientific ownership, mentorship of junior scientists, and potential leadership of projects within an expanding synthetic chemistry and

Formación

• PhD in Chemistry, Chemical Biology, Materials Science, or a related discipline with strong publications.
• Exceptional candidates from oligonucleotide chemistry or adjacent fields may apply; direct oligonucleotide synthesis experience not required.

Responsabilidades

• Design and synthesize novel oligonucleotide medicines and delivery-enabling conjugations and chemistries.
• Collaborate with formulation, cell biology, immunology, and in vivo biology teams to translate chemistries into in vivo candidates.
• Lead independent projects, establish new synthetic/analytical approaches, and mentor junior scientists.

Conocimientos

Solid-Phase Synthesis

Oligonucleotide Delivery

Bioconjugation Chemistry

Analytical Chemistry

Educación

PhD in Chemistry, Chemical Biology, Materials Science

Herramientas

LC-MS

HPLC

AEX

SEC

GPC

Descripción del empleo

Autonomous Therapeutics, Inc. is seeking a Senior/Principal Scientist in Rockville, MD, to drive the design and synthesis of next-generation oligonucleotide medicines.

You will develop delivery-conjugation strategies and work closely with formulation, biology, and in vivo teams to translate chemistry into therapeutic candidates. The role offers high scientific ownership, mentorship of junior scientists, and potential leadership of projects within an expanding synthetic chemistry and