Senior Scientist, Integrated Computational and Experimental Inflammation Discovery

Amgen Inc. (IR); South San Francisco (CA); Ibrido; USD 131.000 - 177.000; Tempo pieno

Vantaggi offerti da questo lavoro

Retirement plan

Medical/dental/vision coverage

Life and disability insurance

Flexible spending accounts

Annual bonus

Stock-based incentives

Time-off plans

Flexible work model

Descrizione del lavoro

Amgen Inc. is seeking a Senior Scientist in Integrated Computational and Experimental Inflammation Discovery to lead scientific activities within inflammation programs, integrating bench work with computational workflows to deepen disease understanding and guide hypotheses.

You will coordinate cross-disciplinary teams, develop novel approaches, mentor colleagues, and contribute to publications and patents while advancing translational biology in inflammation.

Competenze

• Advanced understanding of inflammation/immunology and drug discovery.
• Ability to lead scientific activities within multidisciplinary teams.
• Experience with computational biology, AI-enabled tools, and data analytics.
• Strong communication and ability to mentor colleagues.

Mansioni

• Independently design, execute, analyze, and interpret bench experiments addressing biological questions.
• Apply computational, AI-enabled, and data-analytic approaches for mechanistic insight.
• Develop decision criteria and provide data-driven go/no-go recommendations.
• Lead work groups and coordinate contributions across disciplines.
• Develop novel approaches to improve discovery program outcomes.
• Build expertise in small- and large-molecule inflammation drug discovery.
• Mentor colleagues and contribute to scientific excellence.
• Communicate project data and recommendations across teams.
• Contribute to publications, patents, and technical documents.

Conoscenze

Inflammation biology

Computational biology

Data analysis

AI-enabled tooling

Project coordination

Mentoring

Formazione

PhD

PharmD

MD

Master's degree + 3 years relevant experience

Bachelor's degree + 5 years relevant experience

Descrizione del lavoro

Career Category Scientific Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity‑related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award‑winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Scientist, Integrated Computational and Experimental Inflammation Discovery

What you will do

Let’s do this. Let’s change the world. In this vital role you will help advance Inflammation discovery programs by leading scientific activities within project teams, generating rigorous experimental and computational evidence, and applying innovative technologies to deepen disease understanding and inform therapeutic hypotheses. Working independently and under minimal direction, you will contribute to target program teams and technology/capability development by iterating between bench experimentation and computational workflows. You will coordinate team efforts, develop subject‑matter expertise, and deliver data‑driven recommendations that influence project and program direction.

Key Responsibilities

• Independently design, execute, analyze, and interpret bench/wet‑lab experiments that address critical biological questions, test therapeutic hypotheses, and support target identification, validation, and progression.
• Apply advanced experimental, computational, AI‑enabled, and data‑analytic approaches to generate mechanistic insight, improve experimental design, and integrate findings across data sources.
• Develop decision criteria and provide evidence‑based recommendations for target and program go/no‑go decisions.
• Lead activities within work groups and project teams, coordinating contributions from multiple disciplines to achieve program objectives.
• Develop and implement novel scientific approaches, technologies, and workflows that improve efficiency, rigor, translational relevance, and probability of success in discovery programs.
• Build expertise in small‑ and large‑molecule drug discovery and apply this knowledge to support high‑caliber biological research and therapeutic strategy in Inflammation.
• Proactively develop and optimize solutions to complex scientific or technical problems within area of expertise using ingenuity, creativity, and current scientific knowledge.
• Coach and provide scientific or technical guidance to colleagues within work groups and project teams, contributing to a connected, inclusive culture of scientific excellence.
• Organize, interpret, adapt, and communicate project data and scientific recommendations across projects, functions, and internal scientific forums; contribute to external scientific communications where appropriate.
• Contribute to scientific publications, presentations, patents, technical reports, and other documents that expand organizational knowledge and advance portfolio impact.

Basic Qualifications

• Doctorate degree PhD OR PharmD OR MD [and relevant post‑doc where applicable] OR Master’s degree and 3 years of relevant scientific experience OR Bachelor’s degree and 5 years of relevant scientific experience

Preferred Qualifications

• Advanced and proficient understanding of technical principles, theories, and concepts relevant to inflammation, immunology, disease biology, and drug discovery.
• Demonstrated ability to work independently under minimal direction, determine methods and procedures for new assignments, and make independent scientific decisions within a work group or function.
• Experience leading scientific activities within project teams or work groups and contributing to multidisciplinary teams at the functional, departmental, or therapeutic‑area level.
• Strong track record designing, executing, analyzing, and interpreting experimental studies that support target discovery, validation, translational biology, or therapeutic hypothesis testing.
• Experience applying computational biology, AI‑enabled scientific tools, advanced data analytics, multimodal data integration, or predictive modeling to improve discovery research.
• Ability to proactively develop novel processes, technologies, workflows, or scientific approaches to solve complex problems and improve project outcomes.
• Experience coaching, mentoring, or providing scientific and technical advice to colleagues within work groups or project teams.
• Strong written and verbal communication skills, including the ability to organize, interpret, adapt, and present scientific or technical information across projects and functions.
• Contributions to scientific or technical documents such as posters, presentations, publications, regulatory documents, patent applications, technical reports, or internal governance materials.
• Basic knowledge of related and adjacent disciplinary areas, such as translational science, human genetics, clinical biology, computational biology, protein engineering, small‑molecule discovery, or therapeutic development.

What you can expect from us

From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan
• Stock‑based long‑term incentives
• Award‑winning time‑off plans
• Flexible work models where possible.

Refer to the Work Location Type in the job posting to see if this applies.

Sponsorship

Sponsorship for this role is not guaranteed.

Equal Opportunity

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law. We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation. Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.

Salary Range

131,028.35USD -177,273.65 USD

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen.