Scientist – Inflammation Research

Amgen; Thousand Oaks (CA); On-site; USD 115,000 - 156,000; Full time

Benefits offered by this job

Retirement plan

Medical, dental and vision coverage

Stock-based incentives

Flexible work models

Job summary

Amgen is seeking a Scientist in inflammation research in Thousand Oaks, CA. The role involves conducting in vitro and in vivo experiments, including organoid and air-liquid interface primary cultures, and testing targets in mouse models of inflammatory disease.

You will analyze lung epithelium function, repair, and regeneration, collaborating with a cross-functional team to advance inflammation programs and publish findings.

Qualifications

• Basic Qualifications require Doctorate or Masters with biology experience or Bachelor’s with biology experience.
• PhD preferred with strong background in epithelial biology and inflammation.
• Experience with both in vitro and in vivo experiments is expected.

Responsibilities

• Perform both in vitro and in vivo experiments.
• Generate high-quality data to support target identification and validation in inflammation research.
• Propose drug targets for respiratory diseases using human genetics and literature.
• Apply AI-driven approaches to generate mechanistic insights and guide experiments.
• Publish and present findings at conferences.

Skills

In vitro experiments

In vivo experiments

Organoid cultures

Air-liquid interface

Genomics analysis

Education

Doctorate degree

Master’s degree with 2 years of Biology/Biomedical experience

Bachelor’s degree with 4 years of Biology/Biomedical experience

Job description

Career Category Scientific Job Description

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist – inflammation research

What you will do Let’s do this. Let’s change the world. In this vital role you will perform in vitro and in vivo experiments- including determination of effects of drug targets using organoid and air liquid interface primary cell cultures and testing novel drug targets in mouse models of inflammatory disease. This position will also involve analysis of lung epithelium function, repair, and regeneration. You will collaborate with a dynamic research team from multiple Amgen functional areas.

Key Responsibilities

• Perform both in vitro and in vivo experiments.
• Generate high-quality experimental data to support target identification, validation and progression of Inflammation research programs.
• Propose drug targets for respiratory diseases integrating human genetics, in vitro/in vivo studies, and published literature.
• Use AI-driven approaches to generate mechanistic insights, refine therapeutic hypotheses, and guide experimental design.
• Ability to balance scientific rigor with urgency and adaptability in a dynamic research environment.
• Publish and present at conferences.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Scientist we seek is a researcher with these qualifications.

Basic Qualifications

• Doctorate degree OR Master’s degree and 2 years of Biological Sciences / Biomedical Sciences experience OR Bachelor’s degree and 4 years of Biological Sciences / Biomedical Sciences experience

Preferred Qualifications

• PhD with strong background and research experience in epithelial biology and inflammation.
• Experience performing both in vitro and in vivo experiments.
• Expertise in 2D and 3D primary cell cultures / co-cultures / human tissue cultures and mouse disease models.
• Technical expertise in mouse respiratory disease models and measurement of pulmonary mechanics.
• Strong publication record or significant contributions to therapeutic development programs.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including, but not limited to, relevant skills, experience, and qualifications.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible

Refer to the Work Location Type in the job posting to see if this applies.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Equal Opportunity

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law. We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.

. Salary Range 115,393.45USD -156,120.55 USD

About Amgen

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

For more information, visit www.amgen.com and follow us on www.twitter.com/amgen