Senior Scientist, Inflammation: Human Data & AI Biology

Amgen; Thousand Oaks (CA); On-site; USD 180,000 - 260,000; Full time

Benefits offered by this job

Competitive benefits package

Discretionary annual bonus

Stock-based long-term incentives

Flexible work models

Job summary

Amgen is seeking a Principal Scientist in Inflammation Human Data & Computational Biology to accelerate discovery with deep wet-lab and AI/ML expertise. You will drive mechanistic insights by integrating diverse data sources and guiding experimental design.

We expect senior researchers with PhD/MD/PharmD and substantial industry experience in inflammation/immunology, able to navigate collaborative, matrixed environments and deliver data-driven strategies for therapeutic opportunities.

Qualifications

• PhD in biology, life sciences, or related field.
• MD/PhD with industry experience in Inflammation/Immunology is preferred.
• Industry experience in inflammation research is required for some tracks.
• Advanced proficiency in integrating wet-lab work with computational methods.

Responsibilities

• Continuously apply AI-driven and agentic approaches to generate mechanistic insights and guide experimental design.
• Design, execute, analyze, and interpret studies on disease mechanisms and therapeutic hypotheses.
• Generate high-quality experimental data to support target identification and progression of inflammation programs.
• Integrate experimental results with literature, human genetics, and clinical observations to inform decisions.
• Present data-driven findings to project teams and governance forums.
• Maintain thorough documentation and contribute to knowledge sharing.
• Foster scientific curiosity, collaboration, and operational excellence.

Skills

AI/ML

Computational biology

Wet-lab biology

Data interpretation

Cross-functional collaboration

Education

PhD

PharmD

MD

Master’s degree

Bachelor’s degree

Job description

Amgen is seeking a Principal Scientist in Inflammation Human Data & Computational Biology to accelerate discovery with deep wet-lab and AI/ML expertise. You will drive mechanistic insights by integrating diverse data sources and guiding experimental design.

We expect senior researchers with PhD/MD/PharmD and substantial industry experience in inflammation/immunology, able to navigate collaborative, matrixed environments and deliver data-driven strategies for therapeutic opportunities.