Senior Scientist, Induced Proximity & Target Validation

BioSpace; Brisbane (CA); On-site; USD 162,000 - 209,000; Full time

Job summary

Nurix Therapeutics is seeking a scientist to support its non-degradative induced proximity research strategy. You will design, execute, and troubleshoot biochemical, biophysical, and cell-based assays to interrogate mechanisms and inform go/no-go decisions.

You will partner with chemistry, biology, and biochemistry teams to identify targets, validate mechanisms, and advance candidate optimization, influencing platform strategy and project milestones.

Qualifications

• Ph.D. in biology, biochemistry, molecular biology, or a related field.
• 5+ years of industry drug discovery experience, including induced proximity modalities.

Responsibilities

• Design, execute, troubleshoot bench experiments to interrogate induced proximity mechanisms.
• Develop and validate biochemical, biophysical, and cell-based assays for ternary complex formation.
• Collaborate cross-functionally with chemistry, biology, and biochemistry teams to drive program decisions.
• Present data and recommendations to project teams and senior leadership.

Skills

Biochemical assay development

Biophysical assay development

Cell-based pharmacology

Protein interaction analysis

Data analysis & QC

Cross-functional collaboration

Scientific communication

Education

Ph.D. in biology/biochemistry/molecular biology or related field

5+ years in industry drug discovery

Tools

GraphPad Prism

Job description

Nurix Therapeutics is seeking a scientist to support its non-degradative induced proximity research strategy. You will design, execute, and troubleshoot biochemical, biophysical, and cell-based assays to interrogate mechanisms and inform go/no-go decisions.

You will partner with chemistry, biology, and biochemistry teams to identify targets, validate mechanisms, and advance candidate optimization, influencing platform strategy and project milestones.