Senior Scientist, In Vivo Pharmacology

Bristol-Myers Squibb; Georgia; On-site; USD 90,000 - 150,000; Full time

Job summary

An established industry player is seeking a Senior Scientist in In Vivo Pharmacology to join their innovative Neuroscience TRC team. This role involves planning and implementing studies to evaluate novel delivery technologies and therapeutic modalities for neurodegenerative diseases. With a focus on collaboration and cutting-edge research, you will work alongside some of the brightest minds in biopharma. The position offers unique opportunities for professional growth and the chance to contribute to life-changing therapeutics that transform patients' lives. If you are passionate about advancing science and making a difference, this role is for you.

Benefits

Competitive Benefits

Flexible Work Environment

Opportunities for Professional Growth

Qualifications

• 7+ years of experience in drug discovery research.
• Hands-on experience in in vivo pharmacology and animal models.
• Experience leading drug discovery programs.

Responsibilities

• Plan and implement studies for evaluating novel delivery technologies.
• Maintain transgenic and other animal models for drug candidate evaluation.
• Collaborate with interdisciplinary teams for drug discovery.

Skills

In Vivo Pharmacology

Drug Discovery Research

Animal Handling

Surgical Techniques

Communication Skills

Education

Bachelor's Degree

Master's Degree

Ph.D. in Life Sciences

Tools

Transgenic Animal Models

Blood-Brain Barrier Technologies

Job description

Senior Scientist, In Vivo Pharmacology

Senior Scientist, In Vivo Pharmacology

Apply locations: Cambridge Crossing - MA - US | Time type: Full time | Posted on: Posted 2 Days Ago | Job requisition id: R1591505

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept.

Areas of interest include, but are not limited to, the identification of disease modifying and symptomatic therapies for neurodegenerative, neuro-inflammatory neuropsychiatric and neuromuscular diseases; approaches to modulate protein clearance and reduce or eliminate toxic protein production; emerging technologies (RNA, DNA targeting) that when matched to underlying causal human biology may deliver a precision medicine portfolio with a high probability of translational success; AI/ML in target identification drug discovery; neuroimaging and fluid biomarkers to track disease progression and target engagement; novel blood brain-barrier technologies to enhance delivery of biotherapeutics and genetic medicines across the blood-brain barrier.

Here, you’ll get the chance to grow and thrive through uncommon opportunities and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Position Summary:

The Neuroscience Thematic Research Center (Neuro TRC) leverages external collaborations and internal research to establish a diverse portfolio targeting unmet needs in neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular diseases. The Senior Scientist, Neuroscience Discovery, in collaboration with other members of the Neuroscience TRC, undertakes implementation of in vivo and in vitro studies that enable rapid progression of drug candidates from target identification through clinical proof-of-concept. This position is based in Cambridge, MA, and will join a team of scientists responsible for supporting our collaborative drug discovery mission.

Position Responsibilities:

In this laboratory-based role as a Senior Scientist, in vivo Pharmacology, the ideal candidate will:

• Plan and implement studies designed to evaluate novel BBB delivery technologies and therapeutic modalities applied to diseases of strategic interest to the Neuroscience TRC
• Maintain transgenic and other animal models to evaluate and select drug candidates for further investment
• Serve as project team member for programs employing novel delivery technologies for neurodegenerative and neuromuscular disorders

Experience =

Basic Qualifications:

• Bachelor’s Degree
• 7+ years of academic and / or industry experience

Or

• Master’s Degree
• 5+ years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences
• 2+ years of academic and / or industry experience

Preferred Qualifications:

• PhD with 4+ years of experience in drug discovery research spanning small molecule, biotherapeutics and genetic medicines discovery, with an emphasis on the evaluation of novel delivery technologies and approaches to enhance CNS delivery of therapeutic agents, using genetically modified animals where appropriate
• Hands-on experience in in vivo pharmacology, including small animal handling, surgical techniques, maintenance and breeding of transgenic animal colonies, coordination of research activities and external partnerships
• Experience working as part of an interdisciplinary drug discovery team
• Experience creating and applying genetically engineered animal models of neurologic disease towards identification of novel therapeutics
• Experience leading drug discovery programs from ideation to delivery of a therapeutic candidate
• Expertise in blood-brain-barrier delivery technologies spanning bi-specific antibodies and genetic medicines
• Experience contributing to external collaborations and partnerships
• Excellent oral and written communication skills
• Ability to work both independently and as part of multidisciplinary teams

#LI-Onsite

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients’ lives through science,” every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles, the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

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