Senior Scientist, In-vivo CAR-T

Scorpion Therapeutics; Spring House (PA); On-site; USD 120,000 - 170,000; Full time

Job summary

Scorpion Therapeutics in Spring House, PA seeks a Senior Scientist for In vivo CAR‑T and LVV drug product process development from early to late stages. You will design experiments, collaborate with modelling teams, and perform hands‑on lab work to optimize processes and enable manufacturing transfer per GMP.

Ideal candidates hold a Ph.D. with 0–2 years or a BS/MS with 4–6 years in Life Sciences or Chemical Engineering, with LVV experience and a strong GMP mindset.

Qualifications

• Ph.D. with 0-2 years’ experience or B.S./M.S. with 4-6 years’ relevant experience in Life Sciences or Chemical Engineering.

Responsibilities

• Design and execute process development studies for LVV and CAR‑T applications.
• Collaborate with modelling and data science teams to inform experimentation.
• Perform hands‑on laboratory work for process optimization and characterization.
• Support scale‑up, manufacturing transfer, and GMP‑compliant documentation.

Skills

Viral vector process development

Viral vector formulation

GMP principles

Education

Ph.D. with 0-2 years

B.S./M.S. with 4-6 years

Job description

Role: Senior Scientist, In‑vivo CAR‑T, supporting development and scale‑up of lentiviral vector (LVV) drug product processes from early to late‑stage development.

Responsibilities

Responsibilities include designing and executing process development studies, collaborating with modelling and data science teams, performing hands‑on laboratory work for process optimization, and supporting process characterization, scale‑up, and manufacturing transfer. The role involves cross‑functional collaboration with Analytical Development, MSAT, Quality, Manufacturing, and Regulatory teams, as well as documentation per GxP standards.

Qualifications

Qualifications: Ph.D. with 0-2 years’ experience or B.S./M.S. with 4-6 years’ relevant experience in Life Sciences or Chemical Engineering, with expertise in viral vector process development, viral vector formulation, and GMP principles.

Preferred skills

Preferred skills include experience with LVV platforms, process validation, and late‑stage development activities.

High‑Value

High‑Value: focus on viral vector bioprocessing, gene therapy modalities, early to late development, process scale‑up, and technology transfer in a GMP environment.

Work setup

Work setup: on‑site in Spring House, PA.