Senior Scientist, In-Vivo CAR-T LVV Process Development

Johnson & Johnson Innovative Medicine; Spring House (PA); On-site; USD 120,000 - 180,000; Full time

Job summary

Johnson & Johnson Innovative Medicine is seeking a Senior Scientist, In-vivo CAR-T, based on-site in Spring House, PA. The role focuses on the development, optimization, and scale-up of LVV drug product processes from early to late-stage development, combining hands-on lab work with cross-functional collaboration to ensure robust, GMP-ready processes.

The candidate will design LVV studies, collaborate with modelling and data science teams, and contribute to technology transfer and manufacturing

Qualifications

• Ph.D. with 0–2 years’ experience, or B.S./M.S. with 4–6 years’ experience in Life Sciences or Chemical Engineering.
• Relevant experience in process development of viral vectors and/or LVV formulation development.
• Strong hands-on laboratory experience in drug product or viral vector development.

Responsibilities

• Design and execute LVV process development studies across early and late development stages.
• Collaborate with modelling experts and data scientists to reduce experimental burden and define design space.
• Perform hands-on laboratory work including process design, optimization, and characterization.
• Analyze and interpret data to support process understanding and decision-making.
• Support process characterization activities and technology transfer to internal sites or CMOs.
• Collaborate with Analytical Development, MSAT, Quality, Manufacturing, and Regulatory teams to align on strategy and execution.
• Document experimental work and results per GxP and data integrity requirements.
• Participate in troubleshooting and continuous process improvement initiatives.

Skills

Analytical Reasoning

Biochemistry

Chemistry

Manufacturing

Quality Assurance

CMC

Critical Thinking

Drug Discovery Development

Molecular Diagnostics

Pharmacogenetics

Process Improvements

Scientific Research

Education

Ph.D.

B.S.

M.S.

Job description

Johnson & Johnson Innovative Medicine is seeking a Senior Scientist, In-vivo CAR-T, based on-site in Spring House, PA. The role focuses on the development, optimization, and scale-up of LVV drug product processes from early to late-stage development, combining hands-on lab work with cross-functional collaboration to ensure robust, GMP-ready processes.

The candidate will design LVV studies, collaborate with modelling and data science teams, and contribute to technology transfer and manufacturing