Senior Scientist I - CHO Cell Line Engineering

BioSpace; South San Francisco (CA); On-site; USD 140,000 - 190,000; Full time

Benefits offered by this job

Paid time off

Medical/dental/vision insurance

401(k)

Job summary

AbbVie is seeking a Senior Scientist I to lead CHO cell line development for recombinant antibodies. You will design vector constructs, engineer host cells, and perform transfections to improve titer in stable lines. Collaboration with biology, analytics, and purification teams is essential.

Role requires hands-on wet-lab work, critical thinking, and independent execution with strong data interpretation and scientific communication.

Qualifications

• Must have hands-on experience in molecular/cell biology and recombinant protein expression.

Responsibilities

• Conceive designs to improve CHO expression in vector and host cells.

Skills

Literature review & synthesis

Independent data analysis

Vector improvement design

Mammalian protein expression theory

Scientific communication

multitasking & timelines

Education

BS in molecular biology/related field

MS in molecular biology/related field

PhD in relevant discipline

Tools

Geneious Prime

CRISPR/Cas

transfection

Octet

ViCell

CloneSelect Imager

Beacon

ddPCR/RT-qPCR

Job description

AbbVie is seeking a Senior Scientist I to lead CHO cell line development for recombinant antibodies. You will design vector constructs, engineer host cells, and perform transfections to improve titer in stable lines. Collaboration with biology, analytics, and purification teams is essential.

Role requires hands-on wet-lab work, critical thinking, and independent execution with strong data interpretation and scientific communication.