Senior Scientist, Genomic Sample Prep & DNA Extraction

Nabsys 2.0, LLC

Providence (RI)

Sur place

USD 140 000 - 210 000

Plein temps

Il y a 3 jours
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Avantages offerts par ce poste

Competitive salary
Equity stake
Health, dental, vision, 401(k) plan +
Unlimited vacation
Life insurance

Résumé du poste

Nabsys is seeking a Senior Scientist to lead DNA extraction and input sample compatibility development within the Assay Development group. This hands-on role will define the range of sample types compatible with our genome mapping workflow, from DNA isolation through sample preparation chemistry, and will drive the project end-to-end as a bench-based individual contributor.

You will design, execute, and troubleshoot experiments, optimize extraction methods, evaluate diverse biospecimens, and

Qualifications

  • PhD in biochemistry or molecular biology with 3+ years of industry experience in genomics or biotechnology.
  • Strong knowledge of DNA extraction and manipulation techniques using enzymatic reactions.
  • Experience extracting high-molecular-weight genomic DNA (gDNA) from diverse biological sources.
  • Familiarity with methods for assessing DNA integrity and fragment length (e.g., Qubit, TapeStation, Fragment Analyzer, Femto Pulse, pulsed-field gel electrophoresis).
  • Strong desire to remain bench-based, personally executing experiments while providing technical leadership.
  • Demonstrated ability to drive development projects independently and coordinate work with cross-functional partners.

Responsabilités

  • Own development projects from design to implementation, establishing and extending compatibility of input material types with sample prep chemistry.
  • Design, execute, and troubleshoot bench experiments, generating primary data to drive decisions.
  • Optimize DNA extraction and preparation chemistry to accommodate sample types and improve workflow performance.
  • Evaluate a broad range of biospecimen types across collection and storage conditions and assess impact of pre-analytical variables on DNA quality.
  • Serve as the primary technical contact for input sample type and DNA isolation questions.
  • Maintain awareness of DNA extraction technologies and long-read sequencing platforms.
  • Perform data analysis to interpret results, identify trends, and inform next steps.
  • Communicate findings and recommendations to cross-functional teams and stakeholders.
  • Prepare clear presentations and reports to align progress with objectives.

Connaissances

DNA extraction
Bench-based
Data analysis
Cross-functional coordination
Scientific communication
Experiment design
Technical leadership

Formation

PhD in Biochemistry or Molecular Biology

Outils

KingFisher
Chemagic
Hamilton
Tecan

Description du poste

Nabsys is seeking a Senior Scientist to lead DNA extraction and input sample compatibility development within the Assay Development group. This hands-on role will define the range of sample types compatible with our genome mapping workflow, from DNA isolation through sample preparation chemistry, and will drive the project end-to-end as a bench-based individual contributor.

You will design, execute, and troubleshoot experiments, optimize extraction methods, evaluate diverse biospecimens, and

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