Senior Scientist Functional Genomics

Millipore Corporation; Billerica (MA); On-site; USD 97,000 - 160,000; Full time

Benefits offered by this job

Health insurance

PTO

Retirement contributions

Other perquisites

Job summary

EMD Serono in MA is hiring a functional genomics scientist to join the Discovery Biology group in RU-N&I at our state-of-the-art facility in Billerica, MA. We collaborate with international teams to discover drugs for neurodegenerative and autoimmune diseases, using gene editing to validate targets and generate cellular models.

You will plan in vitro studies, leverage CRISPR and single-cell approaches, and work with diverse readouts (NGS, imaging, FACS).

Qualifications

• PhD in a life science field (e.g., Biology, Biotechnology, Genetics, etc.)
• Masters degree in a life science field with 6+ years of lab experience AND 2+ years with complex cell culture systems and primary cells or iPSCs or CRISPR screens

Responsibilities

• Plan, execute and lead in vitro studies using complex cell systems
• Apply advanced CRISPR techniques to identify and validate targets
• Use pooled, arrayed, and single-cell functional genomics methods
• Work with NGS, imaging, and FACS readouts to study gene roles
• Develop cellular models and assays with disease biology experts
• Record data in ELN and present to labs, teams, and external meetings

Skills

CRISPR gene editing

Cell culture

Molecular biology

FACS

NGS

Data analysis

Scientific communication

Collaboration

iPSC differentiation

Education

PhD in life sciences

Masters in life sciences

Tools

Lentiviral vectors

Lentivirus packaging

NGS library prep

High-content imaging

Job description

Work Your Magic with us! Start your next chapter and join EMD Serono. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

EMD Serono is hiring a functional genomics specialist Scientist/Senior Scientist to join the Discovery Biology group within Research Unit Neuroscience & Immunology (RU-N&I) at our state-of-the-art research facility in Billerica, MA. We are building a functional genomics group to collaborate with an international team of scientists, contributing to the discovery of drugs for neurodegenerative/neuroinflammatory and autoimmune diseases. Working with disease biology experts, the functional genomics team will use gene editing methods to identify and validate new targets as well as to generate cell models. Our cross-functional group will explore novel biology and deliver genetic evidence to advance the Neuroscience & Immunology pipeline.

What you'll do:

• Independently plan, execute and lead in vitro studies using complex cell systems
• Leverage your skills in advanced CRISPR techniques and cell biology to identify and validate new targets and advance our pipeline
• Use pooled, arrayed, and single cell functional genomics methods to interrogate disease biology at scale
• Work with a range of NGS, imaging, and FACS-based readouts to explore the roles of candidate genes in neurologic and immunologic disease
• Work with disease biology experts to develop cellular models and assays
• Record data accurately in an Electronic Laboratory Notebook and maintain records per company policy and legal requirements
• Prepare data reports and present to lab heads, project teams, and at external meetings
• Provide technical support to colleagues in own area of expertise when necessary
• Work closely with members in RU-N&I to support departmental goals

Who You Are:

Minimum Qualifications:

• PhD in a life science field, (e.g., Biology, Biotechnology, Genetics, etc.)
• Masters Degree in a life science field (e.g., Biology, Biotechnology, Genetics, etc.) with 6+ years of lab academic or industry experience AND2+ years' experience with complex cell culture systems and primary cells or iPSCs 2+ years using and designing gene editing tools for high throughput applications and hands-on execution of pooled or arrayed CRISPR or siRNA screens

Preferred Qualifications:

• Background in immunology or neuroscience, with experience working with in vitro cell systems e.g. iPSC differentiation or immune cell isolation
• Experience analyzing and disseminating data to support key decision making
• Broad experience in molecular and cellular biology, including Multicolored FACS and analysis
• High-content imaging and analysis NGS library preparation
• Single cell omics data generation and principals of analysis
• Lentiviral vector design and experience packaging and using lentivirus for gene expression
• Reporter construct design
• Familiarity with documentation practices in a pharmaceutical or biotechnology discovery setting
• Strong verbal and written communication skills and practiced at communicating research findings to cross-disciplinary teams
• Curious, highly collaborative scientist with enthusiasm for exploring novel biology

Pay Range for this position: $96,600 - 159,600

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses.

Benefits offered:

• health insurance
• paid time off (PTO)
• retirement contributions
• other perquisites

For more information

What we offer:

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!