Senior Scientist Functional Genomics

EMD Serono, Inc.; Billerica (MA); On-site; USD 97,000 - 160,000; Full time

Benefits offered by this job

Health insurance

Paid time off

Retirement contributions

Job summary

EMD Serono is seeking a Functional Genomics Scientist/Senior Scientist to join the Discovery Biology group in RU-N&I at our MA facility. You will build a functional genomics group to identify and validate targets, develop cellular models, and generate genetic evidence to advance the Neuroscience & Immunology pipeline.

Join a cross-functional team and apply CRISPR and other genome editing tools to drive neurodegenerative, neuroinflammatory, and autoimmune disease research.

Qualifications

• PhD in life science field required.
• 2+ years experience with complex cell culture systems and primary cells or iPSCs.

Responsibilities

• Independently plan, execute and lead in vitro studies using complex cell systems.
• Leverage CRISPR techniques and cell biology to identify and validate new targets and advance pipeline.
• Use pooled, arrayed, and single cell functional genomics methods to interrogate disease biology at scale.
• Record data accurately and prepare reports for lab meetings and external forums.
• Collaborate with RU-N&I to support department goals.

Skills

CRISPR techniques

Cell culture

Data analysis

Science communication

Education

PhD in life sciences

Master's with 6+ years experience

Tools

NGS

FACS

Lentiviral vectors

Single cell omics

Job description

Work Your Magic with us! Start your next chapter and join EMD Serono.

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role

EMD Serono is hiring a functional genomics specialist Scientist/Senior Scientist to join the Discovery Biology group within Research Unit Neuroscience & Immunology (RU-N&I) at our state-of-the-art research facility in Billerica, MA. We are building a functional genomics group to collaborate with an international team of scientists, contributing to the discovery of drugs for neurodegenerative/neuroinflammatory and autoimmune diseases. Working with disease biology experts, the functional genomics team will use gene editing methods to identify and validate new targets as well as to generate cell models. Our cross-functional group will explore novel biology and deliver genetic evidence to advance the Neuroscience & Immunology pipeline.

What You’ll Do

• Independently plan, execute and lead in vitro studies using complex cell systems
• Leverage your skills in advanced CRISPR techniques and cell biology to identify and validate new targets and advance our pipeline
• Use pooled, arrayed, and single cell functional genomics methods to interrogate disease biology at scale
• Work with a range of NGS, imaging, and FACS-based readouts to explore the roles of candidate genes in neurologic and immunologic disease
• Work with disease biology experts to develop cellular models and assays
• Record data accurately in an Electronic Laboratory Notebook and maintain records per company policy and legal requirements
• Prepare data reports and present to lab heads, project teams, and at external meetings
• Provide technical support to colleagues in own area of expertise when necessary
• Work closely with members in RU-N&I to support departmental goals

Who You Are

Minimum Qualifications

• PhD in a life science field, (e.g., Biology, Biotechnology, Genetics, etc.)

OR

• Masters Degree in a life science field (e.g., Biology, Biotechnology, Genetics, etc.) with 6+ years of lab academic or industry experience

AND

• 2+ years’ experience with complex cell culture systems and primary cells or iPSCs
• 2+ years using and designing gene editing tools for high throughput applications and hands-on execution of pooled or arrayed CRISPR or siRNA screens

Preferred Qualifications

• Background in immunology or neuroscience, with experience working with in vitro cell systems e.g. iPSC differentiation or immune cell isolation
• Experience analyzing and disseminating data to support key decision making
• Broad experience in molecular and cellular biology, including
  • Multicolored FACS and analysis
  • High-content imaging and analysis
  • NGS library preparation
  • Single cell omics data generation and principals of analysis
  • Lentiviral vector design and experience packaging and using lentivirus for gene expression
  • Reporter construct design
• Familiarity with documentation practices in a pharmaceutical or biotechnology discovery setting
• Strong verbal and written communication skills and practiced at communicating research findings to cross-disciplinary teams
• Curious, highly collaborative scientist with enthusiasm for exploring novel biology

Pay Range for this position: $96,600 - 159,600

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites.

What we offer

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!