Senior Scientist, DMPK

Eisai; Cambridge (MA); On-site; USD 131,000 - 173,000; Full time

Job summary

An innovative pharmaceutical company is seeking a Senior Scientist in DMPK to lead drug metabolism and pharmacokinetics activities. This role involves providing scientific leadership and project management across various stages of drug development. The ideal candidate will have a Ph.D. and extensive experience in DMPK principles, regulatory submissions, and multidisciplinary collaboration. Join a dynamic team dedicated to advancing healthcare solutions and making a significant impact in neurology and oncology. If you are passionate about science and eager to contribute to groundbreaking research, this opportunity is for you.

Qualifications

• 5+ years of industry experience in DMPK.
• Strong expertise in ADME, PK/PD, and IND-enabling studies.

Responsibilities

• Lead DMPK project management for drug discovery and development.
• Collaborate on regulatory compliance and data integrity.

Skills

Communication & Cross-functional Influence

Critical Scientific Thinking

Lab Methodologies & Operations

Mentoring

Resource Management

Scientific Research & Econ Modeling

Education

Ph.D. in pharmacokinetics

Ph.D. in drug metabolism

Ph.D. in pharmaceutical sciences

Job description

At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai's human health care (hhc) mission. We're a growing pharmaceutical company that is breaking through in neurology and oncology, with a strong emphasis on research and development. Our history includes the development of many innovative medicines, notably the discovery of the world's most widely-used treatment for Alzheimer's disease. As we continue to expand, we are seeking highly-motivated individuals who want to work in a fast-paced environment and make a difference. If this is your profile, we want to hear from you.

Position: Senior Scientist, DMPK

The Senior Scientist, DMPK will be responsible for providing scientific leadership and project management support for drug metabolism and pharmacokinetics (DMPK) activities across multiple discovery and development programs. This role will serve as a key DMPK representative for projects at different stages, from early discovery to IND-enabling and clinical development, ensuring the successful integration of DMPK strategies into drug development pipelines.

Essential Functions:

1. Serve as the DMPK project manager and representative for multiple drug discovery and development projects, including internal and collaborative programs.
2. Provide strategic DMPK input and guidance to multidisciplinary project teams, ensuring timely decision-making for project advancement, especially for discovery stage projects.
3. Manage and interpret in vitro and in vivo ADME, PK, and PK/PD data to support lead optimization and candidate selection.
4. Collaborate with internal and external partners to design and execute discovery, IND-enabling DMPK studies, ensuring regulatory compliance and data integrity.
5. Facilitate cross-functional collaboration with global health teams, academic institutions, and external partners on discovery and development projects.
6. Mentor and provide scientific guidance to junior team members, supporting their professional growth and development.
7. Represent the Global Eisai DMPK team in IQ Working group.

Requirements:

• Ph.D. in pharmacokinetics, drug metabolism, pharmaceutical sciences, or a related field with 5+ years of industry experience.
• Strong expertise in DMPK principles, including in vitro and in vivo ADME, PK/PD, and IND-enabling studies.
• Experience with regulatory submissions (IND, NDA) and understanding of FDA and ICH guidelines.
• Proven track record of managing DMPK aspects of drug discovery and development projects.
• Excellent communication and collaboration skills, with experience working in multidisciplinary teams.
• Ability to multitask and manage multiple projects efficiently in a fast-paced environment.

Skills: Communication & Cross-functional Influence, Critical Scientific Thinking, Lab Methodologies & Operations, Mentoring, Resource Management, Scientific Research & Econ Modeling

Salary & Benefits:

The base salary range for the Senior Scientist, DMPK is from $131,100 to $172,100. This position is eligible to participate in Eisai Inc. Annual Incentive Plan. Final pay will depend on experience, education, knowledge, and skills. Employees are eligible for company benefits; for details, visit https://us.eisai.com/careers-at-eisai/benefits.

Eisai is an equal opportunity employer and participates in E-Verify to verify employment eligibility in the U.S. for all new hires.