Senior Scientist, CGT Analytics & Method Transfer

Genetix Biotherapeutics; Boston (MA); On-site; USD 127,000 - 164,000; Full time

Benefits offered by this job

Health insurance

401(k) with employer match

Paid time off and holidays

Tuition reimbursement & loan repayment

Job summary

Genetix Biotherapeutics is seeking a Senior Scientist, Analytical Sciences to provide hands-on technical leadership in analytical development for our gene therapy portfolio. The role designs and executes internal testing for process development and leads transfer of methods to external QC labs, acting as the SME for comparability studies and investigations.

The ideal candidate has deep CGT analytics experience, a track record of assay troubleshooting and tech transfers, and the rigor to bridge

Qualifications

• Ph.D. in Biochemistry, Molecular Biology, Analytical Chemistry, or related field with 2–5 years in biopharma; or M.S. with 6+ years of experience.
• Deep hands-on mastery of CGT analytical techniques (Flow Cytometry, ddPCR/qPCR, Cell‑based Potency assays, ELISA).
• Experience with CD34+ cell lineages and/or viral vector characterization preferred.
• Proven success in developing, optimizing, and transferring assays to external CDMOs/CROs; strong troubleshooting skills.
• Excellent communication of bench data to cross-functional teams.

Responsibilities

• Lead analytical execution to support project milestones and pipeline progression.
• Develop and implement analytical strategies aligned with development milestones and regulatory guidelines.
• Partner with Process Development for rapid, high-quality testing for optimization and comparability studies.
• Transfer analytical methods to external QC laboratories; author transfer protocols and oversee validation.
• Support troubleshooting, OOS/OOT investigations, and root-cause analyses with CDMO/CRO partners.
• Collaborate across CMC to produce reports, SOPs, and data packages for regulatory submissions.

Skills

Flow Cytometry

qPCR/ddPCR

Cell-based Potency Assays

ELISA

CD34+ Cells

Viral Vector Characterization

Education

Ph.D. in Biochemistry or Molecular Biology or Analytical Chemistry

M.S. in related field with 6+ years industry experience

Tools

qPCR instruments

Flow cytometers

ELISA readers

Job description

Genetix Biotherapeutics is seeking a Senior Scientist, Analytical Sciences to provide hands-on technical leadership in analytical development for our gene therapy portfolio. The role designs and executes internal testing for process development and leads transfer of methods to external QC labs, acting as the SME for comparability studies and investigations.

The ideal candidate has deep CGT analytics experience, a track record of assay troubleshooting and tech transfers, and the rigor to bridge