Senior Scientist, Cardiometabolic & Bone Metabolism

BioSpace; Thousand Oaks (CA); On-site; USD 150,000 - 210,000; Full time

Job summary

Amgen is seeking a Senior Scientist in Cardiometabolic Disorders to drive biology research, identify therapeutic targets, and guide drug discovery programs. The role combines bench science with leadership, focusing on osteoporosis and metabolic disease, with opportunities to mentor and advance program milestones.

The candidate will perform mechanistic studies, validate targets with human genetics where possible, and collaborate across functions to deliver robust preclinical data and portfolio

Qualifications

• PhD, PharmD or MD with strong biomedical training and post‑doc experience in bone metabolism and metabolic disease.
• Proven ability to design mechanistic studies and generate reproducible high‑quality data.

Responsibilities

• Conceptualizing and proposing drug targets for bone and cardiometabolic disease.
• Designing and performing in vitro and in vivo experiments; data interpretation.
• Communicating results through written and oral presentations; cross‑functional collaboration.
• Leading and mentoring a team of scientists; contributing to publication efforts.
• Documenting studies in ELN and study reports.
• Advancing therapeutic candidates in Cardiometabolic Portfolio.

Skills

Target ideation

In vivo pharmacology

In vitro pharmacology

Data analysis

Scientific communication

Cross-functional collaboration

Manuscripts and posters

Genetics data mining

Data reproducibility

Education

PhD

PharmD

MD

Masters with bone metabolism experience

Bachelors with bone disease experience

Tools

Immunoblotting

Immunocytochemistry

RT-qPCR

Immunoprecipitation

ELISA

Job description

Amgen is seeking a Senior Scientist in Cardiometabolic Disorders to drive biology research, identify therapeutic targets, and guide drug discovery programs. The role combines bench science with leadership, focusing on osteoporosis and metabolic disease, with opportunities to mentor and advance program milestones.

The candidate will perform mechanistic studies, validate targets with human genetics where possible, and collaborate across functions to deliver robust preclinical data and portfolio