Senior Scientist - Biotransformation

IQVIA; Indianapolis (IN); On-site; USD 64,000 - 134,000; Full time

Job summary

IQVIA Laboratories in Indianapolis, IN seeks a Senior Scientist - Biotransformation to lead in vitro and in vivo metabolite studies, develop analytical methods for drug metabolite analysis, and interpret complex data for high-quality study reporting. The role emphasizes collaboration with cross-functional teams and rigorous scientific rigor to advance translational research.

You will perform metabolite identification with MS/MS, ensure data quality, support planning and regulatory-compliant

Qualifications

• Ph.D./Master’s/Bachelor’s in a related field; or equivalent combo.
• 3 years of relevant experience preferred.
• Experience developing analytical methods for drug metabolite analysis.
• Hands-on MS/MS data collection and interpretation.
• Equivalent education/training may be accepted.

Responsibilities

• Perform in vitro and in vivo metabolite identification studies from planning through reporting.
• Prepare and analyze samples, process data, and troubleshoot analytical challenges.
• Develop analytical methods for drug metabolite analysis under regulatory standards.
• Conduct metabolic profiling and acquire MS/MS data for structure elucidation.
• Compile results and prepare protocols and technical reports.
• Support instrument maintenance and calibration.
• Develop SOPs with senior staff guidance.
• Provide training and guidance to junior team members.

Skills

Metabolite profiling

Mass spectrometry (MS/MS)

Analytical method development

Data interpretation

Regulatory compliance

Education

Ph.D. in chemistry/biochemistry/biology, or related field

Master’s degree

Bachelor’s degree

Tools

MS instrumentation

Job description

We are seeking Senior Scientist - Biotransformation to join IQVIA Laboratories at Indianapolis, IN.

We hire passionate innovators who drive healthcare forward through thoughtful and inclusive collaboration. If you want to discover a career with greater purpose, join us as we transform and accelerate research and development.

Job Summary:

Analyze and report in vitro and in vivo biotransformation studies with a focus on analytical method development, metabolite profiling, and data interpretation. Collaborate with scientific teams to deliver high quality study results, support analytical investigations, and ensure timely project execution.

What You’ll Be Doing:

• Perform in vitro and in vivo metabolite identification studies and support study execution from planning through reporting
• Prepare and analyze samples, process data, and troubleshoot analytical challenges to ensure data quality
• Develop and implement analytical methods for the analysis of drug metabolites under appropriate regulatory compliance standards
• Conduct metabolic profiling and acquire MS/MS data for metabolite structure elucidation and pathway assessment
• Compile, analyze, and interpret study results and prepare protocols, technical reports, and supporting documentation
• Support laboratory instrument maintenance, calibration, fault tracing, and performance evaluation
• Develop laboratory procedures and Standard Practices (SPs) with guidance from senior laboratory staff
• Provide training and technical guidance to junior and newly hired team members
  

What We Are Looking For:

• Ph.D. in chemistry, biochemistry, or biology, or a related field; OR Master’s Degree; OR Bachelor’s Degree
• 3 years of relevant experience preferred
• Experience developing and implementing analytical methods for drug metabolite analysis
• Hands‑on expertise with metabolite profiling, mass spectrometry (MS), and MS/MS data collection and interpretation
• Other equivalent combination of education, training, and experience may be accepted in lieu of degree
  

The Knowledge, Skills and Abilities Needed for This Role:

• Strong knowledge of laboratory equipment and instrumentation, including operation, maintenance, calibration, and troubleshooting
• Excellent organizational, documentation, written, and verbal communication skills with strong attention to detail
• Ability to manage multiple projects, maintain accurate experimental records, work effectively in a team environment, and follow safe laboratory practices
  

What We Offer You:

We put our employees at the center of everything we do and are committed to providing them, and their families, with benefits that meet their diverse and changing needs. We invest in integrated benefits programs and resources to take care of our employees’ physical, mental and emotional, financial and social well‑being so they can thrive at home and at work, at any stage of their well‑being journey.

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com

IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.

The potential base pay range for this role, when annualized, is $64,200.00 - $133,600.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.