Senior Scientist, Antibody Protein Sciences & Platform

Twistbioscience; South San Francisco (CA); On-site; USD 180,000 - 232,000; Full time

Benefits offered by this job

Bonus

Equity

Generous benefits package

Job summary

Twist Bioscience is seeking an Sr. Staff Scientist for Protein Sciences R&D in South San Francisco, onsite. You will lead antibody workflows, optimize expression and purification, and build a team while hands-on bench work remains central.

Deep expertise in monoclonal and bispecific antibodies, Fc biology, and platform development is required. A PhD and 8+ years in protein sciences are preferred; travel to Portland is noted.

Qualifications

• PhD in Cell Biology, Biochemistry, or a closely related field required.
• 8+ years of experience in protein sciences with antibody expression/purification.
• Experience with antibody formats and bispecific architectures preferred.

Responsibilities

• Develop antibody production workflows across formats and purification methods.
• Improve end-to-end antibody development workflow including design, cell line development, and analytics.
• Build and manage a team of scientists and research assistants.
• Independently design and execute experiments; analyze data.
• Prioritize tasks to align with company goals and timelines.
• Document results clearly and communicate findings.

Skills

Monoclonal antibodies

Bispecific antibodies

Antibody engineering

Antibody characterization

Protein expression

Cell biology

Purification

Liquid handling

Automation

Python

Travel readiness

Education

PhD in Cell Biology

PhD in Biochemistry

Tools

Liquid handling systems

Automation

Python

Job description

Twist Bioscience is seeking an Sr. Staff Scientist for Protein Sciences R&D in South San Francisco, onsite. You will lead antibody workflows, optimize expression and purification, and build a team while hands-on bench work remains central.

Deep expertise in monoclonal and bispecific antibodies, Fc biology, and platform development is required. A PhD and 8+ years in protein sciences are preferred; travel to Portland is noted.