Senior Scientist, Analytical Development

Asimov, Inc.; Boston, Northern (MA, KY); Hybrid; USD 140,000 - 200,000; Full time

Job summary

Asimov, Inc. is seeking a Senior Scientist to lead Analytical Sciences, directing development of methods to characterize antibodies and related formats within a growing biotherapeutics platform.

You will mentor junior scientists, collaborate across cross-functional teams, troubleshoot challenging assays, and ensure rigorous, data-driven decision making that aligns with program goals. This role offers opportunities to advance analytical capabilities and contribute to therapeutic design strategies.

Qualifications

• Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 4+ years of relevant biopharma analytical experience, or MS with 7+ years.
• Hands-on experience in analytical method development (HPLC/UPLC, MS, CE, UV) across diverse antibody formats.
• Strong understanding of antibody structural formats and how format-specific architecture shapes analytical strategy.
• Experience mentoring junior scientists and fostering rigorous science.
• Excellent written and verbal communication skills.

Responsibilities

• Lead analytical development efforts, designing experiments to generate actionable results.
• Collaborate with cross-functional teams to share findings and support decision-making.
• Mentor junior scientists in experimental design and problem-solving.
• Maintain transparent communication with project stakeholders about progress, risks, results.
• Develop and apply analytical methods (HPLC/UPLC, MS, CE, UV) for proteins.
• Identify opportunities to improve workflows, throughput, and reproducibility.

Skills

Analytical method development

Collaboration

Mentoring

Problem-solving

Data-driven communication

Written and verbal communication

Education

Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field

M.S. in related field with 7+ years of experience

Tools

HPLC/UPLC

Mass spectrometry (MS)

Capillary electrophoresis (CE)

UV detection

Job description

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform--from cells to software--to enable the design and manufacture of next-generation therapeutics.

We are seeking a Senior Scientist to join our Analytical Sciences team. In this role, you will lead analytical efforts to develop and optimize methods supporting the characterization of antibodies and diverse antibody formats (including bispecifics and other multispecifics, Fc-fusions, and other engineered architectures), proteins, and CGT therapeutics. You will actively collaborate with multiple teams, ensuring that your work and insights are aligned with broader program goals. You will apply your technical skills to address complex analytical challenges, continuously grow your expertise, and contribute to a culture of scientific rigor.

About the Role:

• Lead analytical development efforts for key projects, designing and implementing experiments to generate actionable results.
• Engage with cross-functional teams to share findings, raise critical analytical issues, and support aligned decision-making.
• Manage and mentor junior scientists, focusing on experimental design, problem-solving, and fostering a culture of scientific rigor.
• Ensure transparency and maintain consistent communication with project stakeholders about progress, risks, and results.
• Continuously develop and apply technical skills in analytical method development (HPLC/UPLC, MS, CE, and other protein characterization techniques) to address evolving project needs.
• Identify opportunities to improve workflows, analytical throughput, and reproducibility.

About You:

• Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 4+ years of relevant biopharma analytical experience, or M.S. with 7+ years of relevant experience.
• Hands-on experience in analytical method development (HPLC/UPLC, MS, CE, UV, etc.) across diverse antibody formats, with a willingness and aptitude to rapidly expand technical expertise.
• Strong understanding of antibody structural formats and how format-specific architecture (bispecifics/multispecifics, Fc-fusions, biosimilars, and other engineered constructs) shapes analytical strategy and method selection.
• Strong collaboration and alignment skills, with the ability to communicate findings clearly and maintain transparency with stakeholders.
• Experience mentoring junior scientists, guiding them in experimental design and problem-solving, and fostering a culture of rigorous science.
• Proactive problem-solving mindset, with the ability to apply analytical skills to address complex project challenges.
• Experience engaging across teams and functions, influencing decisions through effective data-driven communication.
• Excellent written and verbal communication skills.

We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.