Senior Scientist, Analytical Development

Asimov; Boston (MA); On-site; USD 140,000 - 190,000; Full time

Job summary

Asimov in Boston is seeking a Senior Scientist to lead analytical development for antibodies and formats such as bispecifics, Fc-fusions, and multispecifics. You will design experiments, generate actionable results, and drive project decisions with data-driven insights.

You will mentor junior scientists, collaborate with cross-functional teams, communicate progress and risks transparently, and apply HPLC/UPLC, MS, CE, and related techniques to address evolving therapeutic programs.

Qualifications

• Ph.D. or MS with relevant biopharma analytical experience and 4+ / 7+ years respectively.
• Hands-on method development across diverse antibody formats (bispecifics, Fc‑fusions, etc.).
• Knowledge of analytical strategies for protein characterization and format‑specific architectures.
• Strong collaboration and clear data‑driven communication with stakeholders.

Responsibilities

• Lead analytical development for key antibody projects and related therapeutics.
• Design experiments to generate actionable results and inform decisions.
• Mentor junior scientists in experimental design and problem solving.
• Communicate progress, risks, and results transparently to stakeholders.
• Apply HPLC/UPLC, MS, CE, and related techniques to evolving programs.

Skills

HPLC/UPLC

Mass spectrometry (MS)

Capillary electrophoresis (CE)

UV detection

Analytical method development

Mentoring

Data-driven decision making

Education

Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field

MS in Analytical Chemistry, Biochemistry, Molecular Biology, or related field

Job description

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.

We are seeking a Senior Scientist to join our Analytical Sciences team. In this role, you will lead analytical efforts to develop and optimize methods supporting the characterization of antibodies and diverse antibody formats (including bispecifics and other multispecifics, Fc-fusions, and other engineered architectures), proteins, and CGT therapeutics. You will actively collaborate with multiple teams, ensuring that your work and insights are aligned with broader program goals. You will apply your technical skills to address complex analytical challenges, continuously grow your expertise, and contribute to a culture of scientific rigor.

About the Role:

• Lead analytical development efforts for key projects, designing and implementing experiments to generate actionable results.

• Engage with cross-functional teams to share findings, raise critical analytical issues, and support aligned decision-making.

• Manage and mentor junior scientists, focusing on experimental design, problem-solving, and fostering a culture of scientific rigor.

• Ensure transparency and maintain consistent communication with project stakeholders about progress, risks, and results.

• Continuously develop and apply technical skills in analytical method development (HPLC/UPLC, MS, CE, and other protein characterization techniques) to address evolving project needs.

• Identify opportunities to improve workflows, analytical throughput, and reproducibility.

About You:

• Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 4+ years of relevant biopharma analytical experience, or M.S. with 7+ years of relevant experience.

• Hands‑on experience in analytical method development (HPLC/UPLC, MS, CE, UV, etc.) across diverse antibody formats, with a willingness and aptitude to rapidly expand technical expertise.

• Strong understanding of antibody structural formats and how format‑specific architecture (bispecifics/multispecifics, Fc‑fusions, biosimilars, and other engineered constructs) shapes analytical strategy and method selection.

• Strong collaboration and alignment skills, with the ability to communicate findings clearly and maintain transparency with stakeholders.

• Experience mentoring junior scientists, guiding them in experimental design and problem‑solving, and fostering a culture of rigorous science.

• Proactive problem‑solving mindset, with the ability to apply analytical skills to address complex project challenges.

• Experience engaging across teams and functions, influencing decisions through effective data‑driven communication.

• Excellent written and verbal communication skills.

We're fueled by a vision to transform biological engineering into a fully‑fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.