Senior Scientist: AI-Driven High-Throughput Assay Development

Promega Corporation; Madison (WI); On-site; USD 120,000 - 165,000; Full time

Job summary

Promega Corporation seeks a PhD-level scientist to support pharma/biotech customers with Promega-enabled assays and cell line development across target engagement, PPI, metabolism, and targeted protein degradation. You will provide scientific leadership and troubleshoot projects in a dynamic team.

You will work on bench-based experiments, miniaturize assays for HTS, and collaborate with program managers and sales to deliver results while embracing AI tools to improve efficiency and

Qualifications

• PhD in a scientific discipline with 2–5 years of postgraduate experience in drug discovery programs or industrial R&D.
• Proficient with automation equipment; familiarity with assay development in small titer format, HTS, validation/counterscreening, and assay transfer is a plus.
• Proficient with Microsoft applications and graphing software.
• Quick to adopt emerging technologies, including AI, to improve efficiency and collaboration.

Responsibilities

• Work at the bench to perform experiments using mammalian cell culture, transfections, cloning, CRISPR, immunoblotting, and flow cytometry to develop luminescence-based assays.
• Miniaturize and validate developed assays to enable high-throughput screening using lab automation.
• Own projects from kickoff to delivery with independent experimental design and timelines.
• Communicate project status and results through client meetings and detailed technical reports.
• Work on several different types of projects at a time.
• Leverage AI and advanced digital tools to accelerate experimental design, optimize assay development strategies, enhance data analysis and decision-making.
• Collaborate with program managers, sales, and other business leaders on project execution.
• Demonstrate inclusion and maintain a safe workspace; act with kindness, curiosity, and respect.
• Embrace Promega's ESI core principles in daily work.
• Understand and comply with ethical, legal, and regulatory requirements applicable to our business.

Skills

AI adoption

Automation equipment

Microsoft applications

Scientific leadership

Education

PhD in a scientific discipline

Tools

Automation equipment

Microsoft applications

Job description

Promega Corporation seeks a PhD-level scientist to support pharma/biotech customers with Promega-enabled assays and cell line development across target engagement, PPI, metabolism, and targeted protein degradation. You will provide scientific leadership and troubleshoot projects in a dynamic team.

You will work on bench-based experiments, miniaturize assays for HTS, and collaborate with program managers and sales to deliver results while embracing AI tools to improve efficiency and