Senior Scientist, ADME/PKPD for ADC Programs

Immunome, Inc.; Bothell (WA); On-site; USD 150,000 - 204,000; Full time

Job summary

Immunome, Inc. is seeking a Scientist II / Senior Scientist in ADME to design and execute nonclinical PK/PKPD/ADME strategies for oncology candidates from discovery through development.

You'll partner with cross-functional teams to deliver high-quality data informing decisions and regulatory submissions. You will work on multiple modalities, with emphasis on ADC programs, reporting to the Executive Director, Head of ADME.

Qualifications

• PhD in a relevant discipline with 0–3 years industry experience in ADCPKPD and ADME, or MS with 5+ years relevant industry experience.
• Experience with ADCs required; additional experience with small molecules, monoclonal antibodies, or other modalities preferred.
• Hands-on expertise in PKPD modeling, PK/TK analysis, and study design.
• Knowledge of both non-regulated and regulated bioanalysis.

Responsibilities

• Perform modeling and simulation, analyze PKPD and PK/TK data, and provide clear interpretation to inform program decisions.
• Design and execute stage-appropriate PKPD and ADME studies to support candidate selection, clinical development, and regulatory submissions.
• Collaborate with cross-functional teams to ensure integration of ADME considerations into program strategy and timelines.
• Participate in Translational Sciences and Development team activities, contributing scientific expertise in ADME.
• Represent the ADME function at internal and external meetings, communicating timelines, data, and implications effectively.
• Maintain awareness of evolving best practices and regulatory expectations in ADME sciences.

Skills

Problem-solving

Communication

Cross-disciplinary collaboration

Education

PhD in a relevant discipline

MS with 5+ years experience

Job description

Immunome, Inc. is seeking a Scientist II / Senior Scientist in ADME to design and execute nonclinical PK/PKPD/ADME strategies for oncology candidates from discovery through development.

You'll partner with cross-functional teams to deliver high-quality data informing decisions and regulatory submissions. You will work on multiple modalities, with emphasis on ADC programs, reporting to the Executive Director, Head of ADME.