Senior Scientist

Tundra Technical Solutions; Cambridge (MA); Hybrid; USD 80,000 - 100,000; Full time

Job summary

Tundra Technical Solutions is seeking a Senior Scientist in Translational Medicine to drive innovative programs in allergy and immunology. The role involves developing biomarker strategies and collaborating across teams to advance precision medicine. Candidates should have a PhD and significant experience in relevant research settings.

Qualifications

• PhD required with 4-6 years of relevant experience.
• Hands-on experience with molecular assays preferred.
• Experience in translational and clinical research is essential.

Responsibilities

• Define and execute biomarker plans for allergy and immunology programs.
• Oversee experimental design and lab-based research.
• Collaborate across internal functions to ensure successful execution.

Skills

Molecular and cellular assays

Data analysis

Interpersonal skills

Communication skills

Documentation

Education

PhD in Allergy and Immunology

Post-doctoral training

Tools

PCR

NGS

Western blotting

Prism

Job description

Tundra Technical Solutions provided pay range

This range is provided by Tundra Technical Solutions. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$130.00/hr - $140.00/hr

Direct message the job poster from Tundra Technical Solutions

Digital Recruiter - Tundra Technical Solutions

Job Title: Senior Scientist, Translational Medicine

Job Category: Research & Development

Location: Cambridge, MA

Job Description:

We are seeking a Senior Scientist, Translational Medicine to support the development of innovative programs in allergy and immunology. This role will focus on defining and executing translational and biomarker strategies for both preclinical and clinical-stage programs. The ideal candidate will bring deep scientific expertise, hands-on technical skills, and the ability to work cross-functionally to advance precision medicine approaches.

Key Responsibilities:

• Define and execute translational and biomarker plans for Blueprint’s preclinical and clinical-stage allergy and immunology programs with a focus on mechanism of action, target engagement, establishment of PK/PD/efficacy relationships, patient selection strategies and understanding mechanisms of intrinsic and acquired resistance.
• Ensure that discovery, pre-clinical and clinical biomarker plans are developed and implemented efficiently and aligned with the strategic needs of the program.
• Perform and/or oversee experimental design, lab-based research, data analysis, data integration and data storage. Independently conduct, optimize, and proactively troubleshoot assays both in-house and with CRO.
• Manage external biomarker analysis at specialty CROs including experimental design, validation, qualification, budgeting, timelines, and oversight of quality and execution during trial conduct.
• Represent Translational Medicine within project/program teams; share scientific and strategic perspectives, generate data to support team needs, meet project/program milestones for TM responsibilities.
• Contribute to the development of clinical protocols, laboratory manuals, regulatory submissions, abstracts, and publications.
• Analyze, interpret, and present integrated scientific results and implications for program strategy to internal and external stakeholders.
• Effectively collaborate across internal functions including discovery, translational, clinical pharmacology, clinical development, data management to ensure successful execution in the clinic.
• Clearly communicate translational strategies, timelines, dependencies, risks, and mitigations to team members.
• Evaluate new technologies and partner with external collaborators to enable exploratory biomarkers
• Regularly present research to Translational Medicine and integrated project teams highlighting implications and opportunities for broader program.

Required Skills and Experience:

• Hands-on experience with molecular and cellular assays development, validation and data analysis is preferred, such as PCR, NGS, Western blotting.
• Extensive experience with state-of-the-art assays, and standard software analytical tools, xlsx, Prism, etc.
• Demonstrated knowledge of clinically relevant biomarker approaches across a range of technology platforms
• Experience working with central laboratories and contract research organizations supporting specialized biomarker analysis
• Familiarity with working in the GxP environment with a focus on quality
• Strong interpersonal and communication skills, with a passion for participating in a fast-paced environment characterized by challenging and rigorous science, and innovative thinking
• Strong oral and written communication skills, as well as excellent documentation and organizational skills are essential
• Familiarity with Companion Diagnostics and personalized medicine development is strongly preferred.
• Familiarity with PK/PD/efficacy relationships and delivering PD readouts for in vivo tumor models is preferred
• A great teammate, who listens effectively and invites response and discussion
• A collaborator who communicates in an open, clear, complete, timely and consistent manner

Education and Experience Requirements:

• PhD in Allergy and Immunology, or related discipline
• Relevant post-doctoral training and/or 4-6 years of relevant experience in a biopharmaceutical research setting
• Minimum of 2 years translational, clinical research experience
• Research experience in Allergies, Asthma, Anaphylaxis or related diseases
• Hybrid schedule (~3 days onsite per week; flexible based on workload).
• Office located in Cambridge, MA.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Contract

Job function

• Job function

  Research and Science

• Industries

  Pharmaceutical Manufacturing and Biotechnology Research

Referrals increase your chances of interviewing at Tundra Technical Solutions by 2x

Get notified about new Postdoctoral Researcher jobs in Cambridge, MA.

Research Scientist, Cell and Gene Therapy Analytical (Contract)

Boston, MA $84,000.00-$117,000.00 4 days ago

Postdoctoral Research Associate, Biology

Greater Boston $50,000.00-$60,000.00 1 month ago

Staff - Research Scientist - Control for Autonomous Systems

Post Doctoral Fellow - Computational Modeling and Machine Learning

Boston, MA $160,000.00-$200,000.00 16 hours ago

Boston, MA $160,000.00-$200,000.00 4 days ago

Pioneering Medicines: Senior Research Associate/Associate Scientist, Translational Research

Postdoctoral Research Fellow - Freeman Lab

Staff - Research Scientist - Optimization Algorithms

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.