SENIOR SCIENTIST- REMOTE

NexPro Technologies Inc; New London (CT); Remote; USD 90,000 - 130,000; Full time

Job summary

NexPro Technologies is seeking a Senior Scientist specializing in Biotransformation for a remote role within their Pharmacokinetics, Dynamics, and Metabolism (PDM) team. This long-term engagement focuses on drug discovery, requiring a PhD or equivalent experience, and offers the chance to work on impactful research. Responsibilities include data analysis, metabolic pathway interpretation, and collaboration for model development. Candidates should have hands-on experience with mass spectrometry and data visualization tools.

Qualifications

• PhD in a relevant field or MS with 2+ years industry experience.
• Strong understanding of human drug metabolism and metabolites.
• Demonstrated experience analyzing HRMS data.

Responsibilities

• Analyze high-resolution mass spectrometry data for small molecule elucidation.
• Collaborate with computational ADME staff on biotransformation research.
• Contribute to data insights and presentations.

Skills

Human drug metabolism enzymes

Common metabolite structures

General organic chemistry

Statistical principles

Analytical skills

Problem-solving skills

Data visualization

Education

PhD in Pharmaceutical Sciences, Chemistry, or Biochemistry

MS with 2+ years relevant experience

Tools

Excel

Spotfire

Tableau

JMP

Job description

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SENIOR SCIENTIST - Biotransformation

Job Description

ROLE SENIOR SCIENTIST - Biotransformation

INDUSTRY Life Sciences

DURATION CONTRACT

LOCATION REMOTE reporting to Groton, CT 06340

INTERVIEW pre-qualifying MS TEAMS conversation

Summary

Our client in Groton, CT, a leader in drug discovery and development, is seeking a Senior Scientist – Biotransformation to join their Pharmacokinetics, Dynamics, and Metabolism (PDM) team focused on small molecule drug discovery. In this role, you will support and guide the understanding of human drug metabolism through curation and interpretation of large-scale experimental metabolite ID data to drive predictive modeling efforts to maximize the value of the curated data. This is a long-term engagement offering the opportunity to contribute to cutting-edge research with real-world therapeutic impact.

This is an 18 month engagement.

Responsibilities

• Analyze high-resolution mass spectrometry data (HRMS), including MS2 fragmentation for small molecule structural elucidation.
• Interpret metabolic pathways using knowledge of human drug-metabolizing enzymes and common metabolite types.
• Collaborate with computational ADME staff to develop and apply computational models to support biotransformation research in small molecule drug discovery.
• Leverage spreadsheets and/or BI tools (e.g., Excel, Spotfire, Tableau, JMP) for data visualization and analysis.
• Apply statistical methods to derive insights from complex datasets.
• Contribute to internal discussions and presentations of data insights and recommendations.
  
  

Required

• PhD in a relevant field (e.g., Pharmaceutical Sciences, Chemistry, Biochemistry) or MS with 2+ years of relevant industry experience.
• Strong understanding of:
• Human drug metabolism enzymes
• Common metabolite structures
• General organic chemistry
• Experimental systems for assaying metabolism
• Demonstrated experience analyzing HRMS data, including MS2 fragmentation patterns.
• Keen interest in computational approaches and data-driven science.
• Proficiency with data visualization tools (Excel, Spotfire, Tableau, JMP).
• Solid foundation in statistical principles (through coursework or practical application).
• Strong analytical and problem-solving skills.

• PREFERRED
• Experience with automated analysis of HPLC-HRMS or HPLC-UV-HRMS datasets.
• Familiarity with HPLC-UV data analysis.
• Proficiency in at least one programming language (e.g., Python, R).
• Be part of a collaborative and innovative team at the intersection of drug metabolism and data science.
• Contribute directly to projects that advance therapeutic development.
• Enjoy opportunities for scientific growth and long-term professional engagement.
  

Company Description

NexPro Technologies offers robust, responsive and value-driven IT consulting and placement services.

NexPro Technologies offers robust, responsive and value-driven IT consulting and placement services.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Contract

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  IT Services and IT Consulting

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