Senior Research Lab Tech: Immunology & Cancer Immunotherapy

Michigan Medicine; Ann Arbor (MI); Hybrid; USD 45,000 - 65,000; Full time

Benefits offered by this job

Medical, dental & vision

2:1 retirement match

Job summary

Michigan Medicine is seeking a highly motivated, full-time Research Lab Technician Senior to support translational research in cancer immunology and immunotherapy development for prostate cancer. The role involves collaborative work on molecular, cellular, and animal studies of immune-cell behavior and anti-tumor activity.

The candidate will culture immune cells and cancer lines, perform ELISA, flow cytometry, RNA work, CRISPR editing, and in vivo studies, while maintaining precise records and

Qualifications

• Bachelor's degree in Biology, Biomedical Sciences, Immunology, or related field with 1–2 years experience (or equivalent).
• Hands-on lab experience with mammalian cell culture and standard molecular/cellular biology techniques.
• Experience with one or more: rodent handling, flow cytometry, ELISA, histology, immunohistochemistry, fluorescence microscopy, qRT-PCR, or western blotting.

Responsibilities

• Maintain and culture primary human immune cells and cancer cell lines.
• Perform cell-based assays to evaluate immune-cell migration, activation, and tumor-cell killing.
• Prepare samples and perform ELISA and other plate-based assays.
• Conduct multicolor flow cytometry and assist with data analysis.
• Perform RNA isolation, cDNA synthesis, qRT-PCR, and western blotting.
• Assist with CRISPR-based gene-editing and validation of cell lines.
• Assist with rodent handling and in vivo prostate cancer studies.
• Process cells/tissues for flow cytometry, histology, IHC, IF.
• Acquire and analyze microscopy images.
• Maintain lab records and assist with data collection/analysis.
• Collaborate with team and core facilities.
• Contribute to lab organization and equipment maintenance.

Skills

Mammalian cell culture

Flow cytometry

ELISA

qRT-PCR

Western blotting

Data analysis

Independent work

Education

Bachelor's degree in Biology/Biomedical Sciences/Immunology

Tools

Flow cytometer

ELISA plate reader

Imaging systems

Job description

Michigan Medicine is seeking a highly motivated, full-time Research Lab Technician Senior to support translational research in cancer immunology and immunotherapy development for prostate cancer. The role involves collaborative work on molecular, cellular, and animal studies of immune-cell behavior and anti-tumor activity.

The candidate will culture immune cells and cancer lines, perform ELISA, flow cytometry, RNA work, CRISPR editing, and in vivo studies, while maintaining precise records and