Senior Research Associate, Protein Engineering & Antibodies

SystImmune, Inc.; Washington (District of Columbia); On-site; USD 70,000 - 90,000; Full time

Job summary

SystImmune in Bothell, WA seeks a Research Associate II or Senior Research Associate to join the Protein Engineering team. You will perform molecular biology techniques and antibody-related workflows to support the development of novel therapeutic antibodies.

The role is full-time onsite in Bothell, WA, with responsibilities spanning cloning, plasmid design, and high-throughput workflows. Strong organizational skills and the ability to work independently are essential.

Qualifications

• Bachelor's or Master's degree in Molecular Biology, Biochemistry, or a related field.
• 2+ years of industry experience for Research Associate II; 5+ years for Senior Research Associate.
• 2+ years hands-on lab experience in molecular biology techniques.
• Experience with antibody-related workflows is a plus.
• Liquid handling automation experience is a plus.
• Experience with next-generation sequencing workflows is a plus.
• Strong organizational skills and attention to detail.
• Ability to work independently and as part of a collaborative team.
• Comfortable working in a dynamic environment with shifting priorities.

Responsibilities

• Perform routine and high-throughput molecular biology techniques, including library preparation, lentiviral vectors, PCR, restriction endonuclease digestion, Gibson Assembly, Golden Gate Assembly, bacterial transformations, and plasmid purification.
• Execute binding analytical assays (BLI, SPR) and ensure accurate data for protein candidates.
• Design mammalian expression plasmids and cloning strategies for proteins and multi-specific antibodies.
• Support high-throughput protein analytics workflows with automation for rapid screening.
• Maintain detailed records of procedures and results in electronic lab notebooks.
• Collaborate with team to support cloning and construct generation for protein expression.
• Assist in troubleshooting and optimizing molecular workflows to improve efficiency.
• Manage multiple tasks in a fast-paced environment.
• Maintain lab organization and inventory of reagents and supplies.

Skills

Molecular biology

Antibody workflows

Automation / liquid handling

Next-generation sequencing

Electronic lab notebooks

Team collaboration

Education

Bachelor's or Master's in Molecular Biology or Biochemistry

2+ years industry experience

Tools

Automation platforms

Liquid handling robots

Job description

SystImmune in Bothell, WA seeks a Research Associate II or Senior Research Associate to join the Protein Engineering team. You will perform molecular biology techniques and antibody-related workflows to support the development of novel therapeutic antibodies.

The role is full-time onsite in Bothell, WA, with responsibilities spanning cloning, plasmid design, and high-throughput workflows. Strong organizational skills and the ability to work independently are essential.