Senior Research Associate, Discovery Biology

BBOT; South San Francisco (CA); On-site; USD 122,000 - 130,000; Full time

Job summary

BBOT is seeking a Senior Research Associate to advance innovative cancer therapeutics. The role involves designing experiments, executing pharmacology assays, and collaborating in a fast-paced environment. Candidates should possess extensive knowledge in cancer biology and relevant research experience, particularly in an oncology setting.

Benefits

Market-competitive total rewards package

Annual performance bonus

Company equity

Generous health benefits

Qualifications

• 5 years' experience with B.A./B.S. or 3 years' post-grad experience.
• Broad knowledge of cancer biology required.
• Experience in oncology drug discovery is advantageous.

Responsibilities

• Independently design and analyze experiments in cancer biology.
• Conduct pharmacology experiments and compound screening.
• Provide scientific leadership to junior team members.

Skills

Research experience in cell/molecular biology

Strong problem-solving skills

Ability to collaborate

Education

B.A./B.S. in Cancer Biology, Genetics, Molecular Biology

Tools

CRISPR

NGS

FACS

Job description

Senior Research Associate, Discovery Biology

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Senior Research Associate, Discovery Biology

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About BridgeBio Oncology Therapeutics

Job Type

Full-time

Description

About BridgeBio Oncology Therapeutics

BBOT is a clinical-stage biopharmaceutical company advancing a next generation pipeline of novel small molecule therapeutics targeting RAS and PI3K malignancies. BBOT completed a $200M private financing with external investors in 2024 with the goal of improving outcomes for patients with cancers driven by the two most prevalent oncogenes in human tumors.

For more information visit bridgebiooncology.com.

Who You Are

This is an exciting opportunity for a highly motivated Senior Research Associate with a strong background in cancer biology to join BBOT’s search for innovative cancer therapeutics. We are looking for a talented and enthusiastic individual who thrives in a collaborative, fast-paced, and growing environment to join our team as a laboratory-based leader.

As a key member of the Oncology Therapeutics Group, you will:

• Play a critical intellectual and technical role in the discovery and development of novel small molecule cancer therapeutics.
• Independently design, conduct, and analyze experiments to advance our understanding of cancer biology and propel drug discovery programs across our oncology pipeline.
• Execute pharmacology experiments (biochemical and cell-based assays) to assess the inhibition or activation of cell signaling in the oncology setting, including in response to small molecule inhibitors.
• Conduct compound screening (including medium- and high-throughput studies) to identify leads and potential combination therapies.
• Develop novel tools (such as genetically engineered cell lines) and assays as needed to support the group’s discovery mission.
• Communicate your findings across seniority levels within and beyond BBOT.
• Collaborate closely with colleagues across scientific functions and departments, providing key scientific expertise and guidance in an interdisciplinary environment.
• Provide scientific and technical leadership to junior team members.
• Keep complete and timely records in electronic lab notebooks.
  
  

Requirements

Education, Experience & Skills Requirements

• B.A./B.S + 5 years’ experience or M.A./M.S. + 3 years’ experience in a relevant discipline (e.g. Cancer Biology, Genetics, Molecular Biology).
• Relevant prior research or industry experience in a cell/molecular biology laboratory, ideally within an oncology setting.
• Broad knowledge of cancer biology and independence in critical thinking and scientific achievement.
• Experience with a broad range of cellular and biochemical techniques, including mammalian tumor cell culture and engineering, CRISPR, RNAi, immuno-blotting, NGS, IF/IHC, and FACS.
• Research experience in oncology drug discovery project teams, cancer cell-based assay design, and assay development is advantageous.
• Strong problem-solving skills and a commitment to continuous learning and development.
• Ability to excel in a highly-collaborative and innovative environment.
• Onsite 5 days a week.
  
  

At BBOT, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BBOT is a multi-state employer, and this salary range may not reflect positions based in other states.

Salary Description

$122,000 - $130,000

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

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