Senior Protein Purification Scientist for Bioconjugates

Zealand Pharma; Cambridge (MA); Hybrid; USD 125,000 - 170,000; Full time

Job summary

Zealand Pharma in Cambridge, MA is seeking a Scientist or Senior Scientist in Protein Purification and Analysis to deliver high-purity protein and bioconjugate samples for downstream mass spectrometry and structural biology studies. You will purify recombinant proteins and their bioconjugates, leveraging SEC, IEX, affinity, RP-HPLC, and CE at analytical and preparative scales.

You will work with analytical characterization methods (MS, biophysical assays, flow cytometry) and help develop

Qualifications

• PhD preferred; postdoc experience considered.
• 2+ years post-degree experience for Scientist; 4+ years for Senior Scientist.
• Hands-on purification using SEC, IEX, affinity, RP-HPLC, CE.
• Experience with ADCs/AOCs or bioconjugates preferred.

Responsibilities

• Purify recombinant proteins, peptides, and bioconjugates at analytical and preparative scales.
• Support purification workflows and analytical characterization.
• Collaborate across cross-functional teams in a new research center.
• Develop automated, high-throughput purification approaches.

Skills

Protein purification

AKTA systems

SEC

IEX

Affinity chromatography

RP-HPLC

CE-based methods

Mass spectrometry

Biophysical analysis

Flow cytometry

Education

PhD in Analytical Chemistry

Protein Engineering

Biochemistry

BS/MS with industry experience

Tools

AKTA pure

AKTA avant

Job description

Zealand Pharma in Cambridge, MA is seeking a Scientist or Senior Scientist in Protein Purification and Analysis to deliver high-purity protein and bioconjugate samples for downstream mass spectrometry and structural biology studies. You will purify recombinant proteins and their bioconjugates, leveraging SEC, IEX, affinity, RP-HPLC, and CE at analytical and preparative scales.

You will work with analytical characterization methods (MS, biophysical assays, flow cytometry) and help develop