Senior Program Manager

Synerg; San Diego (CA); On-site; USD 150,000 - 190,000; Full time

Job summary

Syner-G seeks a Senior Program Manager in San Diego to provide strategic leadership across critical biopharma product development initiatives, spanning research to commercialization. You will partner with executive sponsors, functional leaders, and project teams to align scope, priorities, risks, and milestones.

The ideal candidate has 15+ years managing cross-functional programs in life sciences, regulated environments, and will drive governance, design controls, risk management, and

Qualifications

• 15+ years of progressive program management experience in biotech, life sciences, diagnostics, medical devices or related regulated industries.
• Demonstrated success leading complex cross-functional product development programs from concept through commercialization.
• Experience working in regulated environments with quality, regulatory, manufacturing and commercial functions.
• PMP certification is preferred.

Responsibilities

• Provide senior program management leadership across priority product development initiatives, aligning executive sponsors, functional leaders, project teams, and external stakeholders on scope, priorities, risks, tradeoffs, and key decisions.
• Coordinate cross-functional programs supporting development, validation, and commercialization of products, including library preparation kits and related technologies.
• Develop integrated plans, manage dependencies, track milestones, and ensure alignment across workstreams from concept to commercialization.
• Clarify decision points, identify execution risks, resolve obstacles, and maintain momentum toward strategic objectives.
• Plan, facilitate, and drive outcomes from governance meetings, design reviews, milestone reviews, project team meetings, leadership check-ins, and stakeholder forums.
• Prepare executive dashboards, status reports, and recommendations to support informed decision-making.

Skills

Cross-functional leadership

Program management

Executive communication

Stakeholder management

Regulatory knowledge

Education

Bachelor's degree in Life Sciences / Biotechnology

Advanced degree preferred

Tools

Microsoft Office Suite

Smartsheet

Project management tools

Job description

COMPANY DESCRIPTION:

A career here is life-enhancing.

At Syner-G, we enable our people to build careers that impact positively on their quality of life. Through our expertise, insight, consulting and management skills, we accelerate breakthrough science and delivery of life-enhancing therapies to more patients. We work across a diverse range of clients and projects, supporting many organizations from the most critical phases of the drug discovery and approval process through to commercialization. It is meaningful, varied and thought-provoking work with a strategic emphasis, a solutions-driven approach and significant, real-world outcomes, from science to delivery/success. To learn more about who we are and what drives us, watch our company video here.

Underpinning this mission is a culture that aligns perfectly with what we want to achieve. We enable our people to grow, we support them in their learning and we reward them in so many different ways. In return, they play an instrumental role in maintaining our reputation across the globe as a strategic biopharma product development and delivery partner.

Syner-G was recently honored with BioSpace's prestigious "Best Places to Work" 2026 award, for the third consecutive year, along with many other award-winning programs to make a career here truly life-enhancing. These recognitions are a testament to our commitment to fostering a positive and engaging work environment for our employees, with a particular emphasis on culture, career growth and development opportunities, financial rewards, leadership and innovation.

At Syner-G, we recognize that our team members are our most valuable asset. Join us in shaping the future, where your talents are valued, and your contributions make a meaningful impact.

For more information, visit www.Synergbiopharma.com

POSITION OVERVIEW:

We are seeking a highly experienced Senior Program Manager to provide strategic program leadership, structure, and execution oversight across critical product development initiatives supporting next-generation protein sequencing technologies. This role will serve as a key partner to executive leadership, functional leaders, and project teams, ensuring alignment, accountability, and execution excellence across a portfolio of high-priority programs.

The ideal candidate will have 15+ years of experience leading complex cross-functional product development programs within the life sciences, biotechnology, diagnostics, medical device, or related industries. This individual will bring expertise in governance, product development, design controls, risk management, commercialization readiness, and stakeholder engagement to help accelerate innovation while maintaining organizational alignment and operational discipline.

Success in this role requires a seasoned leader who can navigate ambiguity, drive executive decision-making, establish program structure, and maintain momentum across initiatives spanning research, product development, operations, quality, regulatory, manufacturing, and commercialization functions.

WORK LOCATION:

Travel to client sites may be required up to 100%, based on project demands and client expectations.

KEY RESPONSIBILITIES:

(This list is not exhaustive and may be supplemented and changed as necessary.)

• Provide senior program management leadership across priority product development initiatives, aligning executive sponsors, functional leaders, project teams, and external stakeholders on scope, priorities, risks, tradeoffs, and key decisions.
• Lead and coordinate cross-functional programs supporting the development, validation, and commercialization of innovative products, including library preparation kits and related technologies.
• Drive initiatives from concept through commercialization by developing integrated plans, managing dependencies, tracking milestones, and ensuring alignment across workstreams.
• Advance programs by clarifying decision points, identifying execution risks, resolving obstacles, and maintaining momentum toward strategic objectives.
• Plan, facilitate, and drive outcomes from governance meetings, design reviews, milestone reviews, project team meetings, leadership check-ins, and stakeholder forums.
• Prepare executive-level communications, dashboards, status reports, and recommendations to support informed decision-making.
• Coordinate activities across research, product development, engineering, operations, quality, regulatory, manufacturing, supply chain, and commercial teams.
• Ensure timely completion of key program milestones, design control deliverables, and commercialization readiness activities.
• Establish and maintain program governance processes, risk management frameworks, escalation pathways, and accountability mechanisms.
• Identify, assess, and manage program risks, dependencies, assumptions, and resource constraints, facilitating tradeoff discussions as needed.
• Implement program management best practices, tools, and processes that improve visibility, alignment, predictability, and execution effectiveness.
• Serve as a trusted advisor to leadership by providing strategic insights, execution guidance, and recommendations that support business objectives.

QUALIFICATIONS AND REQUIREMENTS:

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements below are representative of the education, experience, knowledge, skills, and abilities required.

Education

• Bachelor's degree in Life Sciences, Biotechnology, Biochemistry, Biomedical Engineering, Engineering, or a related scientific discipline required.
• Advanced degree (MS, PhD, MBA, or equivalent) preferred.

Technical Experience

• 15+ years of progressive program management experience within biotechnology, life sciences, diagnostics, medical device, pharmaceutical, or related regulated industries.
• Demonstrated success leading complex cross-functional product development programs from concept through commercialization.
• Experience supporting the development and launch of scientific instruments, consumables, assays, reagents, kits, or platform-based technologies preferred.
• Strong understanding of stage-gate product development processes, design controls, risk management, product lifecycle management, and commercialization planning.
• Experience operating in fast-paced, innovation-driven organizations requiring strong organizational leadership and execution discipline.
• Experience working within regulated environments and partnering with quality, regulatory, manufacturing, and commercial functions.
• Advanced proficiency with Microsoft Office Suite, Smartsheet, and project/program management tools.
• Experience developing executive dashboards, program reporting, governance materials, and milestone tracking frameworks.

Knowledge, Skills, and Abilities

• PMP certification preferred.
• Exceptional executive communication, presentation, and facilitation skills.
• Proven ability to influence senior leaders and drive alignment among cross-functional stakeholders without direct authority.
• Strong strategic thinking, problem-solving, and decision-support capabilities.
• Ability to navigate