Senior Process Development Scientist — Flexible Work Model

Amgen; Cambridge (MA); On-site; USD 126,000 - 171,000; Full time

Benefits offered by this job

Retirement plan

Medical, dental and vision coverage

Discretionary annual bonus

Stock-based incentives

Flexible work models

Job summary

Amgen is seeking a Process Development Senior Scientist to invent and develop drug substance manufacturing processes for synthetic and hybrid assets. You will advance technologies, support manufacturing and technology transfer, and contribute to regulatory documentation.

The role requires advanced degrees with substantial industry experience and strong communication skills. The team collaborates across chemistry, engineering, and biology to deliver robust, scalable processes.

Qualifications

• PhD/PharmD/MD or Master’s with 3 years industry experience or Bachelor’s with 5 years industry experience.
• PhD in organic chemistry/biochemistry with specialization in synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, or conjugation chemistry.
• Post-doctoral experience and peer‑reviewed publications encouraged.
• Excellent written and verbal communication skills; ability to multitask and manage complex projects.

Responsibilities

• Invent synthetic routes and develop safe, robust, cost-effective processes for synthetic and hybrid drug substances.
• Advance enabling technologies to accelerate development and improve sustainability and efficiency.
• Support cGMP manufacturing and tech transfer to internal facilities and CMOs.
• Ensure process performance through understanding, modeling, and characterization.
• Provide experimental results, documentation, data interpretation, and recommendations to drug substance teams.
• Collaborate across functions to deliver regulatory documents and filings.
• Stay current in organic and process chemistry as a technical expert.

Skills

Communication skills

Education

Doctorate/MD/PharmD or Master’s +3 years or Bachelor’s +5 years

Job description

Amgen is seeking a Process Development Senior Scientist to invent and develop drug substance manufacturing processes for synthetic and hybrid assets. You will advance technologies, support manufacturing and technology transfer, and contribute to regulatory documentation.

The role requires advanced degrees with substantial industry experience and strong communication skills. The team collaborates across chemistry, engineering, and biology to deliver robust, scalable processes.