Process Development Senior Scientist

Amgen; Cambridge (MA); On-site; USD 126,000 - 171,000; Full time

Benefits offered by this job

Retirement plan

Medical, dental and vision coverage

Discretionary annual bonus

Stock-based incentives

Flexible work models

Job summary

Amgen is seeking a Process Development Senior Scientist to invent and develop drug substance manufacturing processes for synthetic and hybrid assets. You will advance technologies, support manufacturing and technology transfer, and contribute to regulatory documentation.

The role requires advanced degrees with substantial industry experience and strong communication skills. The team collaborates across chemistry, engineering, and biology to deliver robust, scalable processes.

Qualifications

• PhD/PharmD/MD or Master’s with 3 years industry experience or Bachelor’s with 5 years industry experience.
• PhD in organic chemistry/biochemistry with specialization in synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, or conjugation chemistry.
• Post-doctoral experience and peer‑reviewed publications encouraged.
• Excellent written and verbal communication skills; ability to multitask and manage complex projects.

Responsibilities

• Invent synthetic routes and develop safe, robust, cost-effective processes for synthetic and hybrid drug substances.
• Advance enabling technologies to accelerate development and improve sustainability and efficiency.
• Support cGMP manufacturing and tech transfer to internal facilities and CMOs.
• Ensure process performance through understanding, modeling, and characterization.
• Provide experimental results, documentation, data interpretation, and recommendations to drug substance teams.
• Collaborate across functions to deliver regulatory documents and filings.
• Stay current in organic and process chemistry as a technical expert.

Skills

Communication skills

Education

Doctorate/MD/PharmD or Master’s +3 years or Bachelor’s +5 years

Job description

Career Category Operations Job Description

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Scientist

What you will do

Let’s do this. Let’s change the world. In this vital role you will be responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team apply their synthetic training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development.

• Invent synthetic routes and develop safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances
• Advance enabling technologies to accelerate pharmaceutical development and to improve sustainability and process efficiency
• Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers
• Ensure process performance through process understanding, modeling and characterization
• Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc.
• Work cross-functionally to deliver regulatory documents and support regulatory filings
• Serve as a technical expert and keep current in the field of organic and process chemistry
• Work effectively in a multi-disciplinary team of chemists, engineers and attribute scientists
• Work independently in advancing projects and studies within required deadlines.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is highly motivated with these qualifications.

Basic Qualifications

• Doctorate degree PhD OR PharmD OR MD OR Master’s degree and 3 years of industry experience OR Bachelor’s degree and 5 years of industry experience

Preferred Qualifications

• Ph.D. in organic chemistry and/or biochemistry with a specialization in total synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, and/or conjugation chemistry
• Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry
• Track record of peer-reviewed publications and research presentations
• Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
• Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects
• A research summary included with CV is strongly encouraged

What you can expect from us

From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law. We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation. .

Salary Range 126,066.05USD -170,559.95 USD

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen