Process Development Senior Associate

Amgen; Thousand Oaks (CA); On-site; USD 80,000 - 108,000; Full time

Benefits offered by this job

Retirement and Savings Plan

Group medical, dental and vision plans

Life and disability insurance

Flexible spending accounts

Discretionary annual bonus program

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible

Job summary

Amgen seeks a Process Development Senior Associate to join the DSTS group in Thousand Oaks, California. You will collaborate with chemists, engineers, and analysts to advance drug substance development and manufacturing.

You will develop safe, robust processes for synthetic and hybrid substances, support manufacturing transfers, and contribute to regulatory documentation. Strong lab skills and bioconjugation experience are valued. Amgen offers a broad rewards program.

Qualifications

• Master's degree or higher in a relevant field.
• Bioconjugation chemistry experience preferred.
• Ability to work in a chemistry laboratory with minimal supervision.
• Strong analytical data interpretation and communication skills.
• Experience with analytical tools such as NMR, HPLC, and MS is a plus.

Responsibilities

• Collaborate with chemists, process engineers, and attribute scientists to support drug substance development.
• Develop safe, robust, and cost-effective processes for synthetic and hybrid drug substances.
• Support cGMP manufacturing and technology transfer to internal facilities and external CMOs.
• Contribute to drug substance development teams with data and documentation.
• Follow GLP/Lab SOPs and maintain good laboratory documentation practices.

Skills

Bioconjugation chemistry

Analytical techniques

Lab supervision lite

Data interpretation

Effective communication

Education

M.S. in organic chemistry or biochemistry/chemical biology (bioconjugation)

Bachelor's degree + 2 years scientific experience

Associate's degree + 4 years scientific experience

High school diploma/GED + 6 years scientific experience

Tools

NMR

HPLC

MS

IR

Raman

Job description

Career Category Scientific Job Description

Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Associate

What you will do

Lets do this. Lets change the world.

In this vital role you will join Amgen's DSTS group within Process Development (PD) is responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Amgen is currently seeking a talented Process Development Senior Associate to join our Drug Substance Technologies - Synthetics (DSTS) group in Thousand Oaks, California. Senior Associates in our team collaborate with chemists, process engineers, and attribute scientists to support drug substance development and manufacturing from early to late-stage development. The successful candidate will be a highly motivated and team-oriented individual with prior lab-based research experience in bioconjugation. Work within a drug substance team comprised of chemists, engineers, and attribute scientists to solve technical problems Contribute to the development of safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers Support process characterization activities, including process understanding and modeling Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc. Works regularly with a supervisor to advance projects within required deadlines. Work cross-functionally to deliver regulatory documents and support regulatory filings Follows good laboratory documentation practices and standard operating procedures

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. dynamic professional we seek is an individual with these qualifications.

• Master's degree
• Bachelor's degree and 2 years of Scientific experience
• Associate's degree and 4 years of Scientific experience
• High school diploma / GED and 6 years of Scientific experience

• M.S. in organic chemistry or biochemistry/chemical biology with a specialization in bioconjugation chemistry
• Prior bioconjugation experience in the biopharmaceutical or pharmaceutical industry
• Demonstrated ability to work in a chemistry laboratory with minimal supervision
• Ability to independently collect and interpret analytical results (NMR, HPLC, MS, IR, Raman, etc)
• Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on projects
• A research summary included with CV is strongly encouraged

What you can expect of us

From our competitive benefits to our collaborative culture, we will support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible

Salary Range 80,044.50USD -108,295.50 USD

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen