Senior & Principal Scientist — Translational AI for Drugs

Pioneering Intelligence; Cambridge (MA); On-site; USD 146,000 - 236,000; Full time

Benefits offered by this job

Healthcare coverage

Annual incentive program

Retirement benefits

Job summary

Pioneering Intelligence is building AI systems that accelerate translational decision making across Flagship’s portfolio. This forward-deployed role bridges capability to impact by applying PI technologies to translational challenges and business decisions.

The successful candidate will reduce scientific uncertainty behind drug development through mechanistic modeling, quantitative analysis, and transparent uncertainty.

Qualifications

• PhD in life sciences with quantitative experience or quantitative life sciences PhD with 3–7 years in industry.
• Experience building mechanistic models for drug development decisions.
• Ability to translate scientific complexity into actionable recommendations for non-technical audiences.
• Proficiency in Python scientific computing (scipy, numpy, pandas).

Responsibilities

• Produce quantitative opinions across due diligence, milestones, and program decisions.
• Deliver translational predictions with confidence and boundary conditions.
• Quantify probability of pharmacological success across dimensions.
• Translate complexity into actionable recommendations for stakeholders.

Skills

Python computing

Quantitative biology

Communication skills

Program management

Education

PhD in life sciences (quantitative)

Job description

Pioneering Intelligence is building AI systems that accelerate translational decision making across Flagship’s portfolio. This forward-deployed role bridges capability to impact by applying PI technologies to translational challenges and business decisions.

The successful candidate will reduce scientific uncertainty behind drug development through mechanistic modeling, quantitative analysis, and transparent uncertainty.