Senior Principal Scientist, Data Science RWE

Scorpion Therapeutics; Raritan (NJ); Hybrid; USD 140,000 - 200,000; Full time

Job summary

Johnson & Johnson's Innovative Medicine division seeks a Lead RWE expert to steer the portfolio of real-world evidence studies, guiding design, analysis, and interpretation to inform regulatory and clinical decisions.

The role partners with therapeutic area scientists, mentors teams, and develops best practices while advancing tools for rapid, bias-mitigated insights across multiple US sites with hybrid travel.

Qualifications

• Ph.D. in epidemiology or biostatistics.
• 5+ years in biopharma, healthcare, or consulting.
• Expert coding skills in R, Python, or SAS.
• Strong experience with RWD (EHR, claims, registries).
• Adept in data extraction, cleaning, and bias mitigation techniques.
• Excellent communication skills.

Responsibilities

• Manage RWE studies including study design, data feasibility, analysis, programming, and interpretation.
• Create study protocols and statistical analysis plans.
• Lead efforts to mitigate biases using diverse RWD sources.
• Develop and maintain tools for project acceleration.
• Partner with therapeutic area scientists to deliver RWE solutions.

Skills

R

Python

SAS

Data cleaning

Bias mitigation

Communication

Epidemiology

Biostatistics

RWD

Education

Ph.D. in Epidemiology or Biostatistics

Tools

R

Python

SAS

Job description

Role

Lead scientific and technical expert in Real-world Evidence (RWE) within Johnson & Johnson's Innovative Medicine division.

Objectives

Oversee RWE project portfolio, develop best practices, mentor team, and deliver actionable insights to support regulatory and clinical decision-making.

Responsibilities

• manage RWE studies including study design, data feasibility, analysis, programming, and interpretation
• create study protocols and statistical analysis plans
• lead efforts to mitigate biases using diverse RWD sources
• develop and maintain tools for project acceleration
• partner with therapeutic area scientists to deliver RWE solutions

Qualifications

• Ph.D. in epidemiology or biostatistics
• 5+ years in biopharma, healthcare, or consulting
• expert coding skills in R, Python, or SAS
• strong experience with RWD (EHR, claims, registries)
• adept in data extraction, cleaning, and bias mitigation techniques
• excellent communication skills

Preferred

• familiarity with drug discovery, clinical development, especially in oncology, Immunology, or Neuroscience
• experience with regulatory submissions

High-value

• focus on external control arms, hybrid studies, comparative effectiveness, post-hoc RCT analysis
• role involves regulatory interactions

Location

multiple US sites; role likely hybrid with some travel.