Associate Director, Real-World Evidence (RWE Scientist)

MSI Pharma; United States; Hybrid; USD 130,000 - 170,000; Full time

Job summary

A leading pharmaceutical company is seeking an Associate Director, Real-World Evidence Scientist to lead real-world research and oversee epidemiologic studies. This senior role requires an advanced degree (MD, PhD, or MS) with 5+ years of RWE experience in Pharma/Biotech. The successful candidate will have strong skills in SAS, R, and Stata, managing vendor performance, and collaborating across time zones. Apply now for the opportunity to impact evidence planning in a dynamic environment.

Qualifications

• Advanced degree: MD, PhD, or MS in Epidemiology, Biostatistics, Public Health, or related field.
• 5+ years of progressive epidemiology or RWE experience, including at least 5 years in Pharma/Biotech.
• Demonstrated experience leading prospective/Phase IV epidemiologic studies.
• Proficiency with SAS, R, Stata and deep understanding of RWD structures.

Responsibilities

• Lead the design, execution, and analysis of real‑world and observational research studies with methodological rigour.
• Manage in‑flight Phase IV and post‑approval epidemiologic studies and oversee CRO/vendor performance.
• Develop protocols for real‑world studies and pragmatic trials; provide methodological and scientific guidance.

Skills

Epidemiology

RWE experience

SAS

R

Stata

Independent working

Cross-timezone collaboration

Education

MD, PhD, or MS in Epidemiology, Biostatistics, Public Health

Tools

SAS

R

Stata

Job description

Associate Director, Real-World Evidence (RWE Scientist)

Location: Eastern United States (onsite/hybrid initially until onboarding completion)

About the Role

We are supporting our client in the search for a highly experienced Real‑World Evidence (RWE) Scientist at Associate Director level. This senior, hands‑on position provides temporary coverage for ongoing Phase IV and post‑approval RWE studies. The role involves leading real‑world research, managing vendors, and driving EU‑facing evidence planning within a global Medical Affairs organisation. This is an individual contributor role requiring strong scientific judgment and the ability to work autonomously.

Key Responsibilities

• Lead the design, execution, and analysis of real‑world and observational research studies with methodological rigour
• Manage in‑flight Phase IV and post‑approval epidemiologic studies and oversee CRO/vendor performance
• Lead RWE feasibility assessments and contribute to evidence planning, including activities focused on Europe.
• Develop protocols for real‑world studies and pragmatic trials; provide methodological and scientific guidance
• Support evidence reviews, strategic decision‑making, and communication with internal stakeholders.
• Support internal and external scientific communication (readouts, abstracts, posters, manuscripts).
• May contribute to systematic literature reviews (SLRs) and meta‑analyses as required.

Requirements

Essential

• Advanced degree: MD, PhD, or MS in Epidemiology, Biostatistics, Public Health, or related field.
• 5+ years of progressive epidemiology or RWE experience, including at least 5 years in Pharma/Biotech.

Demonstrated experience leading:

• Prospective/Phase IV epidemiologic studies
• Retrospective real‑world data analyses (claims/EHR)
• Proficiency with SAS, R, Stata and deep understanding of RWD structures.
• Ability to step in quickly, work independently, and take ownership with minimal ramp‑up.
• Flexibility for cross‑timezone collaboration (EU and Australia).

Preferred

• Experience supporting regulatory/HTA‑facing RWE deliverables and post‑approval commitments
• Background in vaccines or infectious disease.
• Strong R programming skills, including ability to develop or enhance Shiny apps; experience with RWD extraction/cleaning.
• Experience in global Medical Affairs and oversight of vendors/CROs.