Senior Principal Gifts Strategist - Remote, $5M+ Targets

American Cancer Society, Inc.; Chicago (IL); Remote; USD 190,000 - 225,000; Full time

Job summary

The American Cancer Society, Inc. is seeking a Senior Principal, Principal Gifts to lead fundraising for gifts of 5M+ and above. The role partners with ACS leadership, volunteers, and staff to craft personalized donor strategies and drive transformational philanthropy.

Remote role across the United States, requiring extensive experience in principal giving, portfolio management, and high-level donor engagement with ultra‑high-net-worth individuals. Travel and executive collaboration are expected.

Qualifications

• Bachelor's Degree required; Master's preferred; CFRE encouraged.
• 10+ years of fundraising experience with proven close of 7- to 8-figure gifts.
• Strong relationship management with ultra-high-net-worth individuals and foundations.

Responsibilities

• Manage a portfolio of 15-20 high-net-worth individuals and foundations for 5M+ gifts.
• Collaborate across leadership and enterprise teams to align donor priorities with mission goals.
• Develop cases for support, proposals, and stewardship resources for major gifts.

Skills

Donor pipeline

Major gifts

Principal gifts

Relationship building

Communication skills

Donor engagement

Education

Bachelor's Degree

Master's Degree

CFRE

Tools

Salesforce

Job description

The American Cancer Society, Inc. is seeking a Senior Principal, Principal Gifts to lead fundraising for gifts of 5M+ and above. The role partners with ACS leadership, volunteers, and staff to craft personalized donor strategies and drive transformational philanthropy.

Remote role across the United States, requiring extensive experience in principal giving, portfolio management, and high-level donor engagement with ultra‑high-net-worth individuals. Travel and executive collaboration are expected.