Senior Principal Data Scientist - OR & Forecasting

Johnson & Johnson Co.; Malvern (Chester County); On-site; USD 137,000 - 236,000; Full time

Benefits offered by this job

Vacation 120h/yr

Sick time 40h/yr

Floating holidays 13 days/yr

Long-term incentive plan

Pension/401(k) benefits

Job summary

Johnson & Johnson’s R&D Data, Data Science & AI (DDSAI) seeks a Senior Principal Scientist, Data Science to lead Operations Research and decision-support initiatives across Therapeutics Development & Supply (TDS). This senior IC will develop scalable forecasting, optimization, simulation, and decision-modeling capabilities for portfolio planning, laboratory operations, and clinical supply chain.

The role combines hands-on modeling with technical leadership, engaging with senior stakeholders to

Qualifications

• Ph.D. in Operations Research, Industrial Engineering, Applied Mathematics, Statistics, CS, Engineering or related quantitative field with 8+ years experience; or a master’s with 10+ years.
• Advanced expertise in mathematical optimization (linear/mixed-integer), simulation (Monte Carlo or discrete-event), and forecasting/uncertainty analysis.
• Strong Python hands-on skills and modern software development and model-validation practices.
• Track record delivering quantitative decision-support solutions with sustained adoption.

Responsibilities

• Design, build, validate, and deliver forecasting, optimization, simulation, and decision-support solutions for complex problems.
• Develop portfolio/workload/resource forecasts and quantify uncertainties and sensitivities.
• Create analytics and digital twins linking demand, workflow, capacity, and performance to decisions.
• Provide technical leadership and mentorship in modeling, code quality, and validation.

Skills

Python programming

Operations Research

Forecasting & optimization

Stakeholder communication

Mentorship

Education

Ph.D. in OR / quantitative field

Masters with 10+ years experience

Tools

Monte Carlo simulation

Job description

Johnson & Johnson’s R&D Data, Data Science & AI (DDSAI) seeks a Senior Principal Scientist, Data Science to lead Operations Research and decision-support initiatives across Therapeutics Development & Supply (TDS). This senior IC will develop scalable forecasting, optimization, simulation, and decision-modeling capabilities for portfolio planning, laboratory operations, and clinical supply chain.

The role combines hands-on modeling with technical leadership, engaging with senior stakeholders to