Principal Data Scientist – Clinical AI & RWD Solutions

Johnson & Johnson Co.; Titusville (NJ); Hybrid; USD 117,000 - 201,000; Full time

Job summary

Johnson & Johnson Innovative Medicine seeks a Principal Data Scientist to lead end-to-end analytical solutions for clinical-development and trial-operations problems. You will own solution definition, delivery, adoption, and outcomes across stakeholder groups using ML, GenAI, optimization, and RWD.

Lead data science projects, manage stakeholder expectations, and collaborate with clinical, operational, and data teams to drive measurable use-case outcomes.

Qualifications

• Requires 5+ years leading end-to-end data-science solutions.
• Proficient in Python/SQL, ML, GenAI, NLP, and RWD analytics.
• Experience with multimodal data and time-series modeling.

Responsibilities

• Define end-to-end data-science solutions for business problems.
• Lead predictive modeling, simulations, optimization, and GenAI applications.
• Oversee data integration from EHR, claims, registries, and trial data.
• Mentor junior colleagues and contribute reusable code and patterns.

Skills

Advanced analytics

Data science

GenAI

ML

RWD analytics

Education

Master's degree in CS/engineering/biostatistics or quantitative field

PhD preferred

Tools

Python

SQL

Job description

Johnson & Johnson Innovative Medicine seeks a Principal Data Scientist to lead end-to-end analytical solutions for clinical-development and trial-operations problems. You will own solution definition, delivery, adoption, and outcomes across stakeholder groups using ML, GenAI, optimization, and RWD.

Lead data science projects, manage stakeholder expectations, and collaborate with clinical, operational, and data teams to drive measurable use-case outcomes.